Users input a list of CR and CRdb will display CR-related information.
CR name: Users submit the gene name to query CR, including gene symbol, ENTREZ ID, Protein names, Uniprot accession and Ensembl ID.
NOTE: CRdb will provide a prompt when none of the names entered by the user are CR.
Users input a genomic position and CRdb will identify CR regions overlapping with the submitted region.
1) Chromosome position: chromosome:start-end coordinates (i.e. chr6:26104681-26105191)
Users select the ‘Function type’ and ‘Type’, CRdb will display CRs of the corresponding type.
1) Function type: Select from the following options——Histone modifier, DNA methylator and Chromatin remodeler.
2) Type: Select from the following options——Reader, Writer, Eraser, Unknown and All.
Users submit a gene name and CRdb will identify CRs associated with it via relationships between the CR and associated genes, which are identified under different methods.
1) Method: Target genes are identified as follows——Rose genemapper, BETA, GEINE3, ARANCe, TRRUST and All.
Users select from the above methods; The default strategy: All.
2) Gene symbol: Users submit the genetic symbol of the target gene. Only gene symbol can be supported.
Users submit biosample term name of interest, CRdb will display the information of ChIP-seq samples about the bio-sample.
1) Biosample term name: Users submit the biosample term name, such as K562.