| CR | Function | Accession | Protein_names | ENTREZ_ID | Aliases | PMID | Function type | Histone type | Methytor type | Sample information |
|---|---|---|---|---|---|---|---|---|---|---|
| DNMT1 | DNA modification(DNA methylation);DNA modification(DNA methylation maintain);Maintainins methylation patterns established in development. | P26358 | DNA (cytosine-5)-methyltransferase 1 | 1786 | DNA (cytosine-5-)-methyltransferase 1(DNMT);DNA methyltransferases;DNMT-MBD | 33227819.. | DNA Methylator | Unkown | Writer | |
| HDAC1 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Eraser | Q13547 | Histone deacetylase 1 | 3065 | SWI/SNF_Brm, NuRD, BHC, MeCP1, mSin3A, core HDAC, mSin3A-like complex, RING2-L3MBTL2, CREST-BRG1, LSD-CoREST;Histone deacetylase (HDAC);ATP-dependent chromatin remodelling;HDAC | 31913353.. | Histone Modifier | Eraser | Unkown | |
| EP300 | Histone modification write(Histone acetylation);Histone Modification(Histone acetyltransferases);Acetylates all four core histones, and non-histone proteins like p53 and MyoD;Writer | Q09472 | Histone acetyltransferase (EC 2.3.1.48) | 2033 | E1A binding protein p300;Histone acetyltransferases;Bromo-PHD | 34772733.. | Histone Modifier | Writer | Unkown | |
| HDAC2 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Eraser | Q92769 | Histone deacetylase 2 | 3066 | SWI/SNF_Brg1(I), SWI/SNF_Brg1(II), SWI/SNF_Brm, NuRD, BHC, MeCP1, mSin3A, core HDAC, mSin3A-like complex, RING2-L3MBTL2, LSD-CoREST;Histone deacetylase (HDAC);ATP-dependent chromatin remodelling;HDAC | 19424149.. | Histone Modifier | Eraser | Unkown | |
| KDM5B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3/me2/me1 HDM.;Eraser | Q9UGL1 | Lysine-specific demethylase 5B | 10765 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 34671158.. | Histone Modifier | Eraser | Unkown | |
| KDM1A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));HDM, also demethylates and stabilizes DNMT1.;Eraser | O60341 | Lysine-specific histone demethylase 1A | 23028 | NuRD, BHC, SCL;lysine (K)-specific demethylase (KDM);DNA methyltransferases;Jumonji;Jumonji | 34655521.. | Histone Modifier | Eraser | Unkown | |
| ACTB | Chromatin remodelling cofactor | P60709 | ACTB protein | 60 | BRWS1; PS1TP5BP1 | 29220674 | Chromatin Remodeler | Unkown | Unkown | |
| ACTL6A | Chromatin remodelling cofactor;Required for maximal SMARCA4 activity and for the association of the SWI/SNF complex with chromatin. | O96019 | Actin-like protein 6A | 86 | Arp4; ACTL6; BAF53A; INO80K; ARPN-BETA | 34687603.. | Chromatin Remodeler | Unkown | Unkown | |
| ACTL6B | Chromatin remodelling cofactor | O94805 | Actin-like protein 6B | 51412 | ACTL6; BAF53B | 32312822.. | Chromatin Remodeler | Unkown | Unkown | |
| ACTR3B | Chromatin remodelling | Q9P1U1 | Actin-related protein 3B | 57180 | ARP11; ARP3BETA | 31637768 | Chromatin Remodeler | Unkown | Unkown | |
| ACTR5 | Chromatin remodelling | Q9H9F9 | Actin-related protein 5 | 79913 | Arp5; INO80M | 29643506 | Chromatin Remodeler | Unkown | Unkown | |
| ACTR6 | Chromatin remodelling cofactor | Q9GZN1 | Actin-related protein 6 | 64431 | ARP6; CDA12; hARP6; hARPX; HSPC281; MSTP136 | 26164235.. | Chromatin Remodeler | Unkown | Unkown | |
| ACTR8 | Histone modification read | Q9H981 | Actin-related protein 8 | 93973 | Ino80;Actin | 32503430 | Histone Modifier | Reader | Unkown | |
| ADNP | Chromatin remodelling cofactor;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9H2P0 | Activity-dependent neuroprotector homeobox protein | 23394 | activity-dependent neuroprotector homeobox | 32533114.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| AEBP2 | Histone modification write cofactor(Histone methylation) | Q6ZN18 | Zinc finger protein AEBP2 | 121536 | PRC2;Polycomb Repressive Complex 1 | 33479123.. | Histone Modifier | Writer | Unkown | |
| AICDA | DNA modification(DNA demethylation);DNA modification(DNA methylation editor/eraser);May play a role in DNA demethylation. | Q9GZX7 | Single-stranded DNA cytosine deaminase | 57379 | APOB_mRNA_editosome;cytidine deaminase family;DNA demethylases | 35443279.. | DNA Methylator | Unkown | Eraser | |
| AIRE | Histone modification read, TF | O43918 | Autoimmune regulator | 326 | Bromo-PHD | 26972725.. | Histone Modifier | Reader | Unkown | |
| ALKBH1 | Histone modification;DNA modification(DNA methylation editor/eraser) | Q13686 | Nucleic acid dioxygenase ALKBH1 | 8846 | alkylation repair homolog | 27745969.. | DNA Methylator,Histone Modifier | Unkown | Eraser | |
| ALKBH3 | DNA modification(DNA methylation editor/eraser) | Q8N3C0 | Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 | 221120 | alkylation repair homolog | 32398132.. | DNA Methylator | Unkown | Eraser | |
| ANP32A | Chromatin remodelling cofactor | P39687 | ANP32A protein | 8125 | LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1 | 33208942.. | Chromatin Remodeler | Unkown | Unkown | |
| ANP32E | Histone chaperone, Histone modification read | Q9BTT0 | Acidic leucine-rich nuclear phosphoprotein 32 family member E | 81611 | SWR | 24463511.. | Histone Modifier | Reader | Unkown | |
| APEX1 | DNA modification cofactor(DNA demethylation) | P27695 | DNA-(apurinic or apyrimidinic site) endonuclease | 328 | APE; APX; APE1; APEN; APEX; HAP1; REF1 | 34289138.. | DNA Methylator | Unkown | Eraser | |
| APOBEC1 | DNA modification, RNA modification(DNA demethylation, mRNA editing);DNA modification(DNA methylation editor/eraser) | P41238 | C->U-editing enzyme APOBEC-1 (EC 3.5.4.36) (Apolipoprotein B mRNA-editing enzyme 1) (HEPR) (mRNA(cytosine(6666)) deaminase 1) | 339 | APOB_mRNA_editosome;cytidine deaminase enzyme | 27096365.. | DNA Methylator | Unkown | Eraser | |
| APOBEC2 | DNA modification, RNA modification(DNA demethylation, mRNA editing) | Q9Y235 | C->U-editing enzyme APOBEC-2 (EC 3.5.4.36) (mRNA(cytosine(6666)) deaminase 2) | 10930 | ARP1; ARCD1 | 34571854.. | DNA Methylator | Unkown | Eraser | |
| APOBEC3A | DNA modification, RNA modification(DNA demethylation, mRNA editing) | P31941 | APOBEC3A transcript variant 3 | 200315 | A3A; ARP3; PHRBN; bK150C2.1 | 30059493.. | DNA Methylator | Unkown | Eraser | |
| APOBEC3B | DNA modification, RNA modification(DNA demethylation, mRNA editing) | Q9UH17 | DNA dC->dU-editing enzyme APOBEC-3B | 9582 | A3B; ARP4; ARCD3; PHRBNL; APOBEC1L; bK150C2.2; DJ742C19.2 | 23389445.. | DNA Methylator | Unkown | Eraser | |
| APOBEC3C | DNA modification, RNA modification(DNA demethylation, mRNA editing) | Q9NRW3 | Apolipoprotein B editing enzyme catalytic polypeptide-like 3C | 27350 | A3C; PBI; ARP5; ARDC2; ARDC4; APOBEC1L; bK150C2.3 | 23001005.. | DNA Methylator | Unkown | Eraser | |
| APOBEC3D | DNA modification, RNA modification(DNA demethylation, mRNA editing) | Q96AK3 | DNA dC->dU-editing enzyme APOBEC-3D | 140564 | A3D; ARP6; APOBEC3E; APOBEC3DE | 25330146.. | DNA Methylator | Unkown | Eraser | |
| APOBEC3F | DNA modification, RNA modification(DNA demethylation, mRNA editing) | Q8IUX4 | Apolipoprotein B editing enzyme catalytic polypeptide-like 3F | 200316 | A3F; KA6; ARP8; BK150C2.4.MRNA | 31792451.. | DNA Methylator | Unkown | Eraser | |
| APOBEC3G | DNA modification, RNA modification(DNA demethylation, mRNA editing) | Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G (EC 3.5.4.-) (Deoxycytidine deaminase) | 60489 | A3G; ARCD; ARP9; ARP-9; CEM15; CEM-15; MDS019; bK150C2.7; dJ494G10.1 | 20613846.. | DNA Methylator | Unkown | Eraser | |
| APOBEC3H | DNA modification, RNA modification(DNA demethylation, mRNA editing) | Q6NTF7 | APOBEC3H | 164668 | A3H; ARP10; ARP-10 | 29290613.. | DNA Methylator | Unkown | Eraser | |
| ARID1A | Chromatin remodelling cofactor | O14497 | AT-rich interactive domain-containing protein 1A | 8289 | ELD; B120; OSA1; P270; hELD; BM029; MRD14; hOSA1; BAF250; C1orf4; BAF250a; SMARCF1 | 29736026.. | Chromatin Remodeler | Unkown | Unkown | |
| ARID1B | Histone modification write(Histone ubiquitination) | Q8NFD5 | AT-rich interactive domain-containing protein 1B | 57492 | BAF, nBAF, npBAF, PBAF, SWI/SNF-like_EPAFa, SWI/SNF-like EPAFB, SWI/SNF BRM-BRG1;ATP-dependent chromatin remodelling;CHD-ARID | 34386776.. | Histone Modifier | Writer | Unkown | |
| ARID2 | Chromatin remodelling cofactor;Required for the stability of the SWI/SNF chromatin remodelling complex SWI/SNF-B. | Q68CP9 | AT-rich interactive domain-containing protein 2 | 196528 | p200; BAF200 | 28238438.. | Chromatin Remodeler | Unkown | Unkown | |
| ARID4A | Histone modification write cofactor(Histone acetylation);Bridging molecule to recruit HDACs. | P29374 | AT-rich interactive domain-containing protein 4A | 5926 | mSin3A;Histone deacetylases;CHD-ARID | 35365808.. | Histone Modifier | Writer | Unkown | |
| ARID4B | Histone modification write cofactor(Histone acetylation) | Q4LE39 | AT-rich interactive domain-containing protein 4B | 51742 | mSin3A;CHD-ARID | 34818550.. | Histone Modifier | Writer | Unkown | |
| ARNTL | Histone modification write cofactor, TF( TF activator) | O00327 | Aryl hydrocarbon receptor nuclear translocator-like protein 1 | 406 | Unkown | 31534216.. | Histone Modifier | Writer | Unkown | |
| ASH1L | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K36 HMT. | Q9NR48 | Histone-lysine N-methyltransferase ASH1L | 55870 | ash1 (absent, small, or homeotic)-like;Histone methyltransferases;SET-HMT | 35081333.. | Histone Modifier | Writer | Unkown | |
| ASH2L | Histone modification write cofactor(Histone methylation);H3K4 HMT. Complex with MLL | Q9UBL3 | Set1/Ash2 histone methyltransferase complex subunit ASH2 | 9070 | COMPASS, Menin-associated_HMT, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7, COMPASS-like MLL3,4;Histone methyltransferases;SET-HMT | 31555818.. | Histone Modifier | Writer | Unkown | |
| ASXL1 | Histone modification erase, Polycomb group (PcG) protein(Histone deubiquitination);Associates with PRC2 to promote gene repression. | Q8IXJ9 | Polycomb group protein ASXL1 | 171023 | PR-DUB;Polycomb Repressive Complex 2 | 34699595.. | Histone Modifier | Eraser | Unkown | |
| ASXL2 | Histone modification read | Q76L83 | Putative Polycomb group protein ASXL2 | 55252 | Unkown | 32310225.. | Histone Modifier | Reader | Unkown | |
| ATAD2 | Chromatin remodelling | Q6PL18 | ATPase family AAA domain-containing protein 2 | 29028 | ANCCA; CT137; PRO2000 | 33711386 | Chromatin Remodeler | Unkown | Unkown | |
| ATAD2B | Histone modification read | Q9ULI0 | ATPase family AAA domain-containing protein 2B | 54454 | Bromo-PHD | 33084328.. | Histone Modifier | Reader | Unkown | |
| ATF2 | Histone modification write, TF(Histone acetylation, TF activator);Specifically acetylates H2B and H4 in vitro. | P15336 | Cyclic AMP-dependent transcription factor ATF-2 | 1386 | Histone acetyltransferases | 33133688.. | Histone Modifier | Writer | Unkown | |
| ATF7IP | Histone modification write cofactor(Histone methylation);Mediates MBD1 transcriptional repression, couples H3K9me3 with DNA methylation. | Q6VMQ6 | Activating transcription factor 7-interacting protein 1 | 55729 | DNA methyltransferases | 31217192.. | DNA Methylator,Histone Modifier | Writer | Unkown | |
| ATM | Histone modification write(Histone phosphorylation) | Q13315 | ATM protein | 472 | Unkown | 34102611.. | Histone Modifier | Writer | Unkown | |
| ATN1 | Histone modification erase cofactor | P54259 | Atrophin 1 | 1822 | Unkown | 30827498.. | Histone Modifier | Eraser | Unkown | |
| ATR | Histone modification write(Histone phosphorylation) | Q13535 | Serine/threonine-protein kinase ATR | 545 | Unkown | 28811666.. | Histone Modifier | Writer | Unkown | |
| ATRX | Chromatin remodelling;Nucleosome Positioning and Remodeling(Chromatin remodelling helicase);Thought to regulate deposition of H3.3 at heterochromatic regions of the genome, including telomeres | P46100 | Transcriptional regulator ATRX | 546 | JMS; SHS; XH2; XNP; ATR2; SFM1; MRX52; RAD54; MRXHF1; RAD54L; ZNF-HX | 28666128.. | Histone Modifier,Chromatin Remodeler | Unkown | Unkown | |
| ATXN7 | Histone modification write cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | O15265 | Ataxin-7 | 6314 | SAGA;ataxin 7 | 27296891.. | Histone Modifier | Reader,Writer | Unkown | |
| ATXN7L3 | Histone modification erase cofactor(Histone deubiquitination) | Q14CW9 | Alternative protein ATXN7L3 | 56970 | SAGA | 35192684.. | Histone Modifier | Eraser | Unkown | |
| AURKA | Histone modification write(Histone phosphorylation) | O14965 | Aurora kinase (EC 2.7.11.1) | 6790 | Unkown | 32859993.. | Histone Modifier | Writer | Unkown | |
| AURKB | Histone modification write(Histone phosphorylation) | Q96GD4 | Aurora kinase (EC 2.7.11.1) | 9212 | Unkown | 31000705.. | Histone Modifier | Writer | Unkown | |
| AURKC | Histone modification write(Histone phosphorylation) | Q9UQB9 | Aurora kinase (EC 2.7.11.1) | 6795 | Unkown | 33183966.. | Histone Modifier | Writer | Unkown | |
| BABAM1 | Histone modification erase cofactor(Histone deubiquitination) | Q9NWV8 | BRISC and BRCA1-A complex member 1 | 29086 | BRISC, BRCA1-A | 33545059.. | Histone Modifier | Eraser | Unkown | |
| BAHD1 | Chromatin remodelling | Q8TBE0 | Bromo adjacent homology domain-containing 1 protein | 22893 | 21252314.. | Chromatin Remodeler | Unkown | Unkown | ||
| BANP | Histone modification write(Histone acetylation) | Q8N9N5 | Protein BANP | 54971 | Unkown | 34234345.. | Histone Modifier | Writer | Unkown | |
| BAP1 | Histone modification erase, Polycomb group (PcG) protein(Histone deubiquitination);Catalytic component of the PR-DUB complex, that specifically deubiquitinates H2AK119ub1. | Q92560 | Ubiquitin carboxyl-terminal hydrolase BAP1 | 8314 | PR-DUB;Polycomb Repressive Complex 1 | 28614305.. | Histone Modifier | Eraser | Unkown | |
| BARD1 | Histone modification write(Histone ubiquitination) | Q99728 | BRCA1-associated RING domain protein 1 | 580 | BRCC, BRCA1-A;BRCT | 32094664.. | Histone Modifier | Writer | Unkown | |
| BAZ1B | Histone modification write(Histone phosphorylation);Acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Maintenance of chromatin structures during DNA replication processes. | Q9UIG0 | Tyrosine-protein kinase BAZ1B | 9031 | B-WICH, WINAC;ATP-dependent chromatin remodelling;Bromo-PHD | 31840056.. | Histone Modifier | Writer | Unkown | |
| BAZ2A | Chromatin remodelling, Histone modification erase( Histone deacetylation) | Q9UIF9 | Bromodomain adjacent to zinc finger domain protein 2A | 11176 | NoRC;ATP-dependent chromatin remodelling;Bromo-PHD | 25485837.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| BAZ2B | Histone modification read | Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | 29994 | Bromo-PHD | 32712329.. | Histone Modifier | Reader | Unkown | |
| BCORL1 | Histone modification erase cofactor(Histone deacetylation) | Q5H9F3 | BCORL1 protein | 63035 | BCOR | 33945606.. | Histone Modifier | Eraser | Unkown | |
| BMI1 | Polycomb group (PcG) protein;Maintenance of transcriptional repression of key genes during development. H2AK119ub. | P35226 | Polycomb complex protein BMI-1 | 648 | PCGF4; RNF51; FLVI2/BMI1; flvi-2/bmi-1 | 29035367.. | Histone Modifier | Unkown | Unkown | |
| BPTF | Chromatin remodelling;Histone Modification(K4 reader);Binds H3K4me3. | Q12830 | Nucleosome-remodeling factor subunit BPTF | 2186 | NuRF;bromodomain PHD finger transcription factor;ATP-dependent chromatin remodelling;Bromo-PHD | 27185926.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| BRCA1 | Histone modification write cofactor, Histone modification write cofactor, Histone modification write cofactor, TF, TF(Histone acetylation, Histone methylation, Histone ubiquitination, TF activator, TF repressor) | P38398 | BRCA1 (BRCA1 protein) (Breast cancer 1) (Breast cancer type 1 susceptibility protein) (Truncated breast and ovarian cancer susceptibility protein 1) | 672 | BRCC, BRCA1-A | 33471975.. | Histone Modifier | Writer | Unkown | |
| BRCA2 | Histone modification write(Histone acetylation) | P51587 | BRCA2 | 675 | BRCC | 15343273.. | Histone Modifier | Writer | Unkown | |
| BRCC3 | Histone modification erase(Histone deubiquitination) | P46736 | Lys-63-specific deubiquitinase BRCC36 | 79184 | BRISC, BRCA1-A | 23246432.. | Histone Modifier | Eraser | Unkown | |
| BRD1 | Histone modification read | O95696 | BRD1 protein | 23774 | MOZ/MORF;Bromo-PHD | 27142060.. | Histone Modifier | Reader | Unkown | |
| BRD2 | Histone modification read | P25440 | Bromodomain-containing protein 2 | 6046 | Bromo-PHD | 35410381.. | Histone Modifier | Reader | Unkown | |
| BRD3 | Histone modification read | Q15059 | Bromodomain-containing protein 3 short isoform | 8019 | Bromo-PHD | 32895492.. | Histone Modifier | Reader | Unkown | |
| BRD4 | Histone modification read;Histone Modification(K27 reader) | O60885 | BRD4 protein | 23476 | bromodomain containing;Bromo-PHD | 30466442.. | Histone Modifier | Reader | Unkown | |
| BRD7 | Histone modification read | Q9NPI1 | Bromodomain-containing protein 7 | 29117 | SWI/SNF BRM-BRG1;Bromo-PHD | 32028981.. | Histone Modifier | Reader | Unkown | |
| BRD8 | Histone modification read;Histone Modification(K27 reader) | Q9H0E9 | Bromodomain-containing protein 8 | 10902 | SWR, NuA4, NuA4-related complex;bromodomain containing;Bromo-PHD | 19787264.. | Histone Modifier | Reader | Unkown | |
| BRD9 | Histone modification read | Q9H8M2 | Bromodomain-containing protein 9 | 65980 | SWI/SNF BRM-BRG1;Bromo-PHD | 34586831.. | Histone Modifier | Reader | Unkown | |
| BRDT | Histone modification read | Q58F21 | Bromodomain testis-specific protein | 676 | Bromo-PHD;Bromo-PHD | 33637650.. | Histone Modifier | Reader | Unkown | |
| BRE | Histone modification write cofactor(Histone ubiquitination) | Q9NXR7 | Alternative protein BRE | 9577 | BRISC, BRCC, BRCA1-A | 34458009.. | Histone Modifier | Writer | Unkown | |
| BRMS1 | Chromatin remodelling | Q9HCU9 | Breast cancer metastasis-suppressor 1 | 25855 | 32853985 | Chromatin Remodeler | Unkown | Unkown | ||
| BRMS1L | Histone modification erase(Histone deacetylation) | Q5PSV4 | Breast cancer metastasis-suppressor 1-like protein (BRMS1-homolog protein p40) (BRMS1-like protein p40) | 84312 | mSin3A | 25406648.. | Histone Modifier | Eraser | Unkown | |
| BRPF1 | Histone modification read;Histone Modification(K36 reader) | P55201 | Peregrin | 7862 | MOZ/MORF;bromodomain and PHD finger containing,1;Histone acetyltransferases;Bromo-PHD | 27500495.. | Histone Modifier | Reader | Unkown | |
| BRPF3 | Histone modification write cofactor(Histone acetylation) | Q9ULD4 | Bromodomain and PHD finger-containing protein 3 | 27154 | MOZ/MORF;Bromo-PHD | 26620551.. | Histone Modifier | Writer | Unkown | |
| BRWD1 | Histone modification read | Q9NSI6 | Bromodomain and WD repeat-containing protein 1 | 54014 | Bromo-PHD | 26301565.. | Histone Modifier | Reader | Unkown | |
| BRWD3 | Histone modification read | Q6RI45 | Bromodomain and WD repeat-containing protein 3 | 254065 | Bromo-PHD | 23479607.. | Histone Modifier | Reader | Unkown | |
| BTAF1 | Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | O14981 | BTAF1 protein | 9044 | MOT1; TAF172; TAFII170; TAF(II)170 | 16179647 | Chromatin Remodeler | Unkown | Unkown | |
| BUB1 | Histone modification write(Histone phosphorylation) | O43683 | Mitotic spindle checkpoint kinase | 699 | Unkown | 33248027.. | Histone Modifier | Writer | Unkown | |
| C14orf169 | Histone modification erase(Histone methylation) | Q9H6W3 | Ribosomal oxygenase 1 | 79697 | Unkown | 33745927.. | Histone Modifier | Eraser | Unkown | |
| C17orf49 | Histone modification read | Q8IXM2 | Chromosome 17 open reading frame 49 | 124944 | CHD8, MLL2/3, MLL4/WBP7 | 35587057.. | Histone Modifier | Reader | Unkown | |
| CARM1 | Histone modification write(Histone methylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q86X55 | Histone-arginine methyltransferase CARM1 | 10498 | coactivator-associated arginine methyltransferase 1;PRMT | 27309807.. | Histone Modifier | Reader,Writer | Unkown | |
| CBX1 | Histone modification read | P83916 | Chromobox protein homolog 1 | 10951 | CHD-ARID | 30209216.. | Histone Modifier | Reader | Unkown | |
| CBX2 | Histone modification read | Q14781 | Chromobox protein homolog 2 | 84733 | PRC1;Polycomb Repressive Complex 1;CHD-ARID | 32870972.. | Histone Modifier | Reader | Unkown | |
| CBX3 | Histone modification read;Part of PRC1-like complex 4. Binds the nuclear lamina through lamin B receptor. | Q13185 | Chromobox protein homolog 3 | 11335 | RING2-L3MBTL2, L3MBTL1;Polycomb Repressive Complex 1;CHD-ARID | 29206900.. | Histone Modifier | Reader | Unkown | |
| CBX4 | Histone modification read | O00257 | E3 SUMO-protein ligase CBX4 (EC 2.3.2.-) (Chromobox protein homolog 4) (Polycomb 2 homolog) (Pc2) (hPc2) | 8535 | PRC1;Polycomb Repressive Complex 1;CHD-ARID | 32111827.. | Histone Modifier | Reader | Unkown | |
| CBX5 | Histone modification read;Histone Modification(K9 reader) | P45973 | CBX5 protein | 23468 | chromobox homolog;CHD-ARID | 34458856.. | Histone Modifier | Reader | Unkown | |
| CBX6 | Histone modification read | O95503 | Chromobox protein homolog 6 | 23466 | PRC1;Polycomb Repressive Complex 1;CHD-ARID | 29089522.. | Histone Modifier | Reader | Unkown | |
| CBX7 | Histone modification read;Histone Modification(K36 reader) | O95931 | Chromobox protein homolog 7 | 23492 | PRC1;chromobox homolog;Polycomb Repressive Complex 1;CHD-ARID | 29422082.. | Histone Modifier | Reader | Unkown | |
| CBX8 | Histone modification read;Promotes H3K9me3. Regulates cellular lifespan by repressing CDKN2A. | Q9HC52 | Chromobox protein homolog 8 | 57332 | PRC1;Polycomb Repressive Complex 1;CHD-ARID | 31849331.. | Histone Modifier | Reader | Unkown | |
| CDC6 | Chromatin remodelling | Q99741 | Cell division control protein 6 homolog | 990 | CDC18L; HsCDC6; HsCDC18 | 28703201.. | Chromatin Remodeler | Unkown | Unkown | |
| CDC73 | Histone modification write cofactor(Histone methylation) | Q6P1J9 | Cell division cycle 73 Paf1/RNA polymerase II complex component-like protein isoform 1 | 79577 | Unkown | 35742816.. | Histone Modifier | Writer | Unkown | |
| CDK1 | Histone modification write(Histone phosphorylation) | P06493 | Cyclin-dependent kinase 1 | 983 | Unkown | 33272830.. | Histone Modifier | Writer | Unkown | |
| CDK17 | Histone modification write(Histone phosphorylation) | Q00537 | Cyclin-dependent kinase 17 | 5128 | Unkown | 35168653.. | Histone Modifier | Writer | Unkown | |
| CDK2 | Histone modification write(Histone phosphorylation) | P24941 | Cyclin-dependent kinase 2 | 1017 | Unkown | 24075009.. | Histone Modifier | Writer | Unkown | |
| CDK3 | Histone modification write(Histone phosphorylation) | Q00526 | Cyclin-dependent kinase 3 | 1018 | Unkown | 35533805.. | Histone Modifier | Writer | Unkown | |
| CDK5 | Histone modification write(Histone phosphorylation) | Q00535 | CDK5 protein | 1020 | Unkown | 34814918.. | Histone Modifier | Writer | Unkown | |
| CDK7 | Histone modification write(Histone phosphorylation) | P50613 | Cyclin-dependent kinase 7 (EC 2.7.11.22) (Cell division protein kinase 7) | 1022 | Unkown | 25043025.. | Histone Modifier | Writer | Unkown | |
| CDY1 | Histone modification write(Histone acetylation) | Q9Y6F8 | Testis-specific chromodomain protein Y 1 | 9085 | CHD-ARID | 27725957.. | Histone Modifier | Writer | Unkown | |
| CDY1B | Histone modification write | Q9Y6F8 | Testis-specific chromodomain protein Y 1 | 253175 | CDY | 33766143.. | Histone Modifier | Writer | Unkown | |
| CDY2A | Histone modification write(Histone acetylation) | Q9Y6F7 | Testis-specific chromodomain protein Y 2 | 9426 | CHD-ARID | 33959695 | Histone Modifier | Writer | Unkown | |
| CDY2B | Histone modification write | A1L473 | Chromodomain protein, Y-linked, 2B | 203611 | CDY | 33766143.. | Histone Modifier | Writer | Unkown | |
| CDYL | Histone modification write(Histone acetylation) | Q9Y232 | Chromodomain Y-like protein | 9425 | CHD-ARID | 28803779.. | Histone Modifier | Writer | Unkown | |
| CDYL2 | Histone modification read | Q8N8U2 | Chromodomain Y-like protein 2 | 124359 | CHD-ARID | 32373210.. | Histone Modifier | Reader | Unkown | |
| CECR2 | Histone modification read | Q9BXF3 | Cat eye syndrome critical region protein 2 | 27443 | CERF, CERF;Bromo-PHD | 35108062.. | Histone Modifier | Reader | Unkown | |
| CHAF1A | Chromatin remodelling | Q13111 | Chromatin assembly factor 1 subunit A | 10036 | CAF1; P150; CAF-1; CAF1B; CAF1P150 | 34365742.. | Chromatin Remodeler | Unkown | Unkown | |
| CHAF1B | Chromatin remodelling | Q13112 | Chromatin assembly factor 1 subunit B | 8208 | CAF1; MPP7; CAF-1; CAF1A; CAF1P60; CAF-IP60; MPHOSPH7 | 30423293.. | Chromatin Remodeler | Unkown | Unkown | |
| CHD1 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader);Required for the maintenance of open chromatin and pluripotency in ESC;Remodeler | O14646 | Chromodomain-helicase-DNA-binding protein 1 | 1105 | chromodomain helicase DNA binding protein (CHD);ATP-dependent chromatin remodelling;CHD-ARID | 28166537.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD1L | Chromatin remodelling | Q86WJ1 | Chromodomain-helicase-DNA-binding protein 1-like | 9557 | ALC1; CHDL | 24359616.. | Chromatin Remodeler | Unkown | Unkown | |
| CHD2 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader);SNF2-related helicase/ATPase domains.;Remodeler | O14647 | DNA helicase (EC 3.6.4.12) | 1106 | chromodomain helicase DNA binding protein (CHD);ATP-dependent chromatin remodelling;CHD-ARID | 23708187.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD3 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q12873 | Chromodomain-helicase-DNA-binding protein 3 | 1107 | NuRD;chromodomain helicase DNA binding protein (CHD);ATP-dependent chromatin remodelling;CHD-ARID | 28977666.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD4 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader);Main component of the NuRD/Mi-2 complex;Remodeler | Q14839 | Chromodomain-helicase-DNA-binding protein 4 | 1108 | NuRD;chromodomain helicase DNA binding protein (CHD);ATP-dependent chromatin remodelling;CHD-ARID | 33301730.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD5 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q8TDI0 | Chromodomain-helicase-DNA-binding protein 5 | 26038 | chromodomain helicase DNA binding protein (CHD);CHD-ARID | 24419087.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD6 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q8TD26 | DNA helicase (EC 3.6.4.12) | 84181 | chromodomain helicase DNA binding protein (CHD);CHD-ARID | 30651562.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD7 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader);Remodeler | Q9P2D1 | Chromodomain-helicase-DNA-binding protein 7 | 55636 | chromodomain helicase DNA binding protein (CHD);CHD-ARID | 20130577.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD8 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9HCK8 | DNA helicase (EC 3.6.4.12) | 57680 | CHD8, MLL2/3, MLL4/WBP7;chromodomain helicase DNA binding protein (CHD);CHD-ARID | 27602517.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHD9 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q3L8U1 | Chromodomain-helicase-DNA-binding protein 9 | 80205 | chromodomain helicase DNA binding protein (CHD);CHD-ARID | 25689118.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| CHEK1 | Histone modification write(Histone phosphorylation) | O14757 | Serine/threonine-protein kinase Chk1 | 1111 | Unkown | 34090465.. | Histone Modifier | Writer | Unkown | |
| CHUK | Histone modification write(Histone phosphorylation) | O15111 | Inhibitor of nuclear factor kappa-B kinase subunit alpha (EC 2.7.11.10) (Nuclear factor NF-kappa-B inhibitor kinase alpha) | 1147 | Unkown | 20961246.. | Histone Modifier | Writer | Unkown | |
| CIR1 | Histone modification read | Q86X95 | Corepressor-interacting with RBPJ 1 | 9541 | Unkown | 9771976 | Histone Modifier | Reader | Unkown | |
| CIT | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone phosphorylation) | O14578 | Citron Rho-interacting kinase | 11113 | Unkown | 34112926 | Histone Modifier | Writer | Unkown | |
| CLNS1A | Histone modification write cofactor(Histone methylation) | P54105 | Methylosome subunit pICln (Chloride channel, nucleotide sensitive 1A) (Chloride conductance regulatory protein ICln) | 1207 | methylosome | 34439272 | Histone Modifier | Writer | Unkown | |
| CLOCK | Histone modification write(Histone acetylation);Histone Modification(Histone acetyltransferases) | O15516 | Circadian locomoter output cycles protein kaput | 9575 | clock circadian regulator | 32423353.. | Histone Modifier | Writer | Unkown | |
| CRB2 | Histone modification read | Q5IJ48 | Protein crumbs homolog 2 (Crumbs-like protein 2) | 286204 | Unkown | 31438467.. | Histone Modifier | Reader | Unkown | |
| CREBBP | Histone modification write(Histone acetylation);Histone Modification(Histone acetyltransferases);Critical role in embryonic development, acetylates both histone and non-histone proteins.;Writer | Q92793 | Histone acetyltransferase (EC 2.3.1.48) | 1387 | CREB binding protein;Histone acetyltransferases;Bromo-PHD | 21390130.. | Histone Modifier | Writer | Unkown | |
| CSRP2BP | Histone modification write(Histone acetylation) | Q9H8E8 | Alternative protein CSRP2BP | 57325 | ATAC | 27940555.. | Histone Modifier | Writer | Unkown | |
| CTBP1 | Chromatin remodelling | Q13363 | C-terminal-binding protein 1 | 1487 | BARS | 32075774 | Chromatin Remodeler | Unkown | Unkown | |
| CTBP2 | Histone modification write cofactor(Histone methylation) | P56545 | C-terminal-binding protein 2 | 1488 | Unkown | 34781990.. | Histone Modifier | Writer | Unkown | |
| CTCF | Chromatin remodelling, TF( TF activator);Histone Modification(histone acetyltransferase or deacetylase) | P49711 | Transcriptional repressor CTCF (11-zinc finger protein) (CCCTC-binding factor) (CTCFL paralog) | 10664 | MRD21 | 31905366.. | Chromatin Remodeler | Unkown | Unkown | |
| CTCFL | Chromatin remodelling | Q8NI51 | Transcriptional repressor CTCFL | 140690 | CT27; BORIS; CTCF-T; HMGB1L1; dJ579F20.2 | 32393311.. | Chromatin Remodeler | Unkown | Unkown | |
| CUL1 | Chromatin remodelling cofactor | Q13616 | Cullin-1 | 8454 | 11961546.. | Chromatin Remodeler | Unkown | Unkown | ||
| CUL2 | Chromatin remodelling cofactor | Q13617 | Cullin-2 | 8453 | 35650603.. | Chromatin Remodeler | Unkown | Unkown | ||
| CUL3 | Histone modification write(Histone ubiquitination) | Q13618 | Uncharacterized protein CUL3 | 8452 | Unkown | 31780330.. | Histone Modifier | Writer | Unkown | |
| CUL4A | Histone modification write(Histone ubiquitination) | Q13619 | Cullin-4A | 8451 | Unkown | 28420424.. | Histone Modifier | Writer | Unkown | |
| CUL4B | Histone modification write(Histone ubiquitination) | Q13620 | Cullin-4B | 8450 | Unkown | 31729464.. | Histone Modifier | Writer | Unkown | |
| CXXC1 | Chromatin remodelling, TF | Q9P0U4 | CXXC-type zinc finger protein 1 | 30827 | CFP1; CGBP; SPP1; PCCX1; PHF18; hCGBP; ZCGPC1; HsT2645; 2410002I16Rik; 5830420C16Rik | 33433611 | Chromatin Remodeler | Unkown | Unkown | |
| DAPK3 | Histone modification write(Histone phosphorylation) | O43293 | Death-associated protein kinase 3 | 1613 | Kinases | 33767426.. | Histone Modifier | Writer | Unkown | |
| DDB1 | Histone modification write(Histone ubiquitination) | Q16531 | DNA damage-binding protein 1 | 1642 | Unkown | 25043012.. | Histone Modifier | Writer | Unkown | |
| DDB2 | Histone modification write cofactor(Histone ubiquitination) | Q92466 | DNA damage-binding protein 2 | 1643 | Unkown | 32789493.. | Histone Modifier | Writer | Unkown | |
| DEK | Chromatin remodelling | P35659 | Protein DEK | 7913 | D6S231E | 31107244.. | Chromatin Remodeler | Unkown | Unkown | |
| DHX30 | Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q7L2E3 | RNA helicase (EC 3.6.4.13) | 22907 | DEAH (Asp-Glu-Ala-His) box helicase 30 | 21204022.. | Histone Modifier | Reader | Unkown | |
| DMAP1 | Chromatin remodelling | Q9NPF5 | DNA methyltransferase 1-associated protein 1 | 55929 | EAF2; SWC4; MEAF2; DNMAP1; DNMTAP1 | 30553276 | Chromatin Remodeler | Unkown | Unkown | |
| DNAJC1 | Histone modification write cofactor, Histone modification erase cofactor(Histone acetylation, Histone deacetylation) | Q96KC8 | DnaJ homolog subfamily C member 1 (DnaJ homolog subfamily C member 1 variant 3) (DnaJ homolog subfamily C member 1 variant 4) | 64215 | Unkown | 26480920.. | Histone Modifier | Writer,Eraser | Unkown | |
| DNAJC2 | Histone modification read | Q99543 | DnaJ homolog subfamily C member 2 | 27000 | SANT domain;SANT domain | 32904265.. | Histone Modifier | Reader | Unkown | |
| DNMT3A | DNA modification(DNA methylation);DNA modification(De novo methylation);Genome-wide de novomethylation, essential for the establishment of DNA methylation patterns during development. | Q9Y6K1 | DNA (cytosine-5)-methyltransferase 3A | 1788 | DNA (cytosine-5-)-methyltransferase 3(DNMT);DNA methyltransferases;DNMT-MBD | 29414941.. | DNA Methylator | Unkown | Writer | |
| DNMT3B | DNA modification(DNA methylation);DNA modification(De novo methylation);Genome-wide de novomethylation, essential for the establishment of DNA methylation patterns during development. | Q9UBC3 | DNA cytosine-5--methyltransferase 3 beta transcript variant 9 (EC 2.1.1.37) | 1789 | DNA (cytosine-5-)-methyltransferase 3(DNMT);DNA methyltransferases;DNMT-MBD | 10555141.. | DNA Methylator | Unkown | Writer | |
| DNMT3L | Histone modification read;DNA modification(De novo methylation);Catalytically inactive, but essential for DNMT3A and DNMT3B function. | Q9UJW3 | DNA (cytosine-5)-methyltransferase 3-like | 29947 | DNA (cytosine-5-)-methyltransferase 3(DNMT);DNA methyltransferases | 30321403.. | DNA Methylator,Histone Modifier | Reader | Writer | |
| DNTTIP2 | Chromatin remodelling | Q5QJE6 | Deoxynucleotidyltransferase terminal-interacting protein 2 | 30836 | ERBP; FCF2; TdIF2; HSU15552; LPTS-RP2 | 35370417 | Chromatin Remodeler | Unkown | Unkown | |
| DOT1L | Histone modification write(Histone methylation);Histone Modification(K79 writer);H3K79 HMT | Q8TEK3 | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 84444 | DOT1-like histone H3K79 methyltransferase;Histone methyltransferases;SET-HMT | 30765112.. | Histone Modifier | Writer | Unkown | |
| DPF1 | Chromatin remodelling cofactor | Q92782 | DPF1 protein | 8193 | NEUD4; BAF45b; neuro-d4 | 34696437.. | Chromatin Remodeler | Unkown | Unkown | |
| DPF2 | Chromatin remodelling | Q92785 | Zinc finger protein ubi-d4 | 5977 | REQ; UBID4; ubi-d4 | 30609396.. | Chromatin Remodeler | Unkown | Unkown | |
| DPF3 | Chromatin remodelling | Q92784 | Zinc finger protein DPF3 | 8110 | CERD4; BAF45C | 30824325.. | Chromatin Remodeler | Unkown | Unkown | |
| DPPA3 | Histone modification read | Q6W0C5 | Developmental pluripotency-associated protein 3 | 359787 | Unkown | 33235224.. | Histone Modifier | Reader | Unkown | |
| DPY30 | Histone modification write cofactor(Histone methylation) | Q9C005 | Protein dpy-30 homolog (Dpy-30-like protein) (Dpy-30L) | 84661 | COMPASS, Menin-associated_HMT, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7, COMPASS-like MLL3,4 | 34985972.. | Histone Modifier | Writer | Unkown | |
| DTX3L | Histone modification write(Histone ubiquitination) | Q8TDB6 | E3 ubiquitin-protein ligase DTX3L | 151636 | Unkown | 24886089.. | Histone Modifier | Writer | Unkown | |
| DZIP3 | Histone modification write(Histone ubiquitination) | Q86Y13 | E3 ubiquitin-protein ligase DZIP3 | 9666 | Unkown | 33067265.. | Histone Modifier | Writer | Unkown | |
| EED | Polycomb group (PcG) protein;Histone Modification(histone deacetylation);Different isoforms determine PRC3 or PRC4 PRC2 variants. | O75530 | Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1) | 8726 | HEED; WAIT1 | 25240281.. | Histone Modifier | Unkown | Unkown | |
| EHMT1 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K9me1/me2 HMT. | Q9H9B1 | Histone-lysine N-methyltransferase EHMT1 | 79813 | euchromatic histone-lysine N-methyltransferase;Histone methyltransferases;SET-HMT | 33311485.. | Histone Modifier | Writer | Unkown | |
| EHMT2 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K9me1/me2, H3K27me HMT. | Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | 10919 | euchromatic histone-lysine N-methyltransferase;Histone methyltransferases;SET-HMT | 32174799.. | Histone Modifier | Writer | Unkown | |
| EID1 | Histone modification write cofactor(Histone acetylation) | Q9Y6B2 | EP300-interacting inhibitor of differentiation 1 | 23741 | Unkown | 29789384 | Histone Modifier | Writer | Unkown | |
| EID2 | Histone modification write cofactor(Histone acetylation) | Q8N6I1 | EID2 protein | 163126 | Unkown | 14612439 | Histone Modifier | Writer | Unkown | |
| EID2B | Histone modification erase cofactor(Histone acetylation) | Q96D98 | EP300-interacting inhibitor of differentiation 2B | 126272 | Unkown | 26186194.. | Histone Modifier | Eraser | Unkown | |
| ELP2 | Histone modification write cofactor(Histone acetylation) | Q6IA86 | Elongator complex protein 2 | 55250 | Pol2 elongator | 33976153.. | Histone Modifier | Writer | Unkown | |
| ELP3 | Histone modification write(Histone acetylation) | Q9H9T3 | Elongator complex protein 3 (hELP3) (EC 2.3.1.-) (tRNA uridine(34) acetyltransferase) | 55140 | Pol2 elongator;HAT | 30733442.. | Histone Modifier | Writer | Unkown | |
| ELP4 | Histone modification write cofactor(Histone acetylation) | Q96EB1 | Elongator complex protein 4 | 26610 | Pol2 elongator | 30087688.. | Histone Modifier | Writer | Unkown | |
| ELP5 | Histone modification write cofactor(Histone acetylation) | Q8TE02 | Elongator complex protein 5 | 23587 | Pol2 elongator | 31792210 | Histone Modifier | Writer | Unkown | |
| ELP6 | Histone modification write cofactor(Histone acetylation) | Q0PNE2 | Elongator complex protein 6 | 54859 | Pol2 elongator | 35223903 | Histone Modifier | Writer | Unkown | |
| EMSY | Histone modification write cofactor(Histone methylation) | Q7Z589 | BRCA2-interacting transcriptional repressor EMSY | 56946 | Unkown | 34963055.. | Histone Modifier | Writer | Unkown | |
| ENY2 | Histone modification erase cofactor(Histone ubiquitination) | Q9NPA8 | Transcription and mRNA export factor ENY2 | 56943 | SAGA | 20048002.. | Histone Modifier | Eraser | Unkown | |
| EP400 | Chromatin remodelling, Histone modification write( Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader);Regulates nucleosome stability during DNA repair | Q96L91 | EP400 protein | 57634 | SWR, NuA4, NuA4-related complex;E1A binding protein;ATP-dependent chromatin remodelling;SNF2-5 | 26669263.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | |
| EPC1 | Polycomb group (PcG) protein | Q9H2F5 | Enhancer of polycomb homolog 1 | 80314 | Epl1 | 26350215.. | Histone Modifier | Unkown | Unkown | |
| EPC2 | Chromatin remodelling | Q52LR7 | Enhancer of polycomb homolog 2 | 26122 | EPC-LIKE | 24166297.. | Chromatin Remodeler | Unkown | Unkown | |
| ERCC6 | Chromatin remodelling;Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | Q03468 | Excision repair cross-complementing rodent repair deficiency, complementation group 6 | 2074 | CSB; CKN2; COFS; ARMD5; COFS1; RAD26; UVSS1 | 27231489 | Chromatin Remodeler | Unkown | Unkown | |
| EYA1 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q99502 | Eyes absent homolog (EC 3.1.3.48) | 2138 | eyes absent (EYA) family | 34864618.. | Histone Modifier | Eraser | Unkown | |
| EYA2 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | O00167 | Putative regulatory uORF | 2139 | eyes absent (EYA) family | 34044846.. | Histone Modifier | Eraser | Unkown | |
| EYA3 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q99504 | Eyes absent homolog 3 (EC 3.1.3.48) | 2140 | eyes absent (EYA) family | 29884726.. | Histone Modifier | Eraser | Unkown | |
| EYA4 | Histone modification erase(Histone phosphorylation);Histone Modification(Phosphorylation editor) | O95677 | Eyes absent homolog (EC 3.1.3.48) | 2070 | eyes absent (EYA) family | 31101108.. | Histone Modifier | Eraser | Unkown | |
| EZH1 | Histone modification write, Polycomb group (PcG) protein(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K27me1/me2/me3 HMT. Less critical for H3K27me3 formation than EZH2.;Writer | Q92800 | Histone-lysine N-methyltransferase EZH1 | 2145 | PRC2;enhancer of zeste 1 polycomb repressive complex 2 subunit;Polycomb Repressive Complex 1(Catalytic subunit );SET-HMT | 28512107.. | Histone Modifier | Writer | Unkown | |
| EZH2 | Histone modification write, Polycomb group (PcG) protein(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K27me1/me2/me3 HMT. Major role in stem cell identity maintenance. Also methylates GATA4. Catalytic subunit of PRC2 complex.;Writer | Q15910 | [Histone H3]-lysine(27) N-trimethyltransferase (EC 2.1.1.356) | 2146 | PRC2;enhancer of zeste 2 polycomb repressive complex 2 subunit;Histone methyltransferases;SET-HMT | 26845405.. | Histone Modifier | Writer | Unkown | |
| FAM175B | Histone modification erase cofactor(Histone ubiquitination) | Q15018 | BRISC complex subunit Abraxas 2 | 23172 | BRISC | 30854784 | Histone Modifier | Eraser | Unkown | |
| FBL | Histone modification write(Histone methylation) | P22087 | rRNA 2'-O-methyltransferase fibrillarin | 2091 | Unkown | 31156610 | Histone Modifier | Writer | Unkown | |
| FOXA1 | Chromatin remodelling, TF | P55317 | Hepatocyte nuclear factor 3-alpha | 3169 | HNF3A; TCF3A | 31243370.. | Chromatin Remodeler | Unkown | Unkown | |
| FTO | DNA modification(DNA methylation editor/eraser) | Q9C0B1 | Alpha-ketoglutarate-dependent dioxygenase FTO (EC 1.14.11.53) (Fat mass and obesity-associated protein) (U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO) (U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO) (mRNA (2'-O-methyladenosine-N(6)-)-demethylase FTO) (mRNA N(6)-methyladenosine demethylase FTO) (tRNA N1-methyl adenine demethylase FTO) | 79068 | fat mass and obesity associated | 24247219.. | DNA Methylator | Unkown | Eraser | |
| GABRG1 | Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q8N1C3 | Gamma-aminobutyric acid receptor subunit gamma-1 (GABA(A) receptor subunit gamma-1) | 2565 | gamma-aminobutyric acid (GABA) A receptor, gamma 1 | 10447508.. | Histone Modifier | Reader | Unkown | |
| GADD45A | Chromatin remodelling | P24522 | Growth arrest and DNA damage-inducible protein GADD45 alpha | 1647 | DDIT1; GADD45 | 30617255.. | Chromatin Remodeler | Unkown | Unkown | |
| GADD45B | Chromatin remodelling | O75293 | Growth arrest and DNA damage-inducible protein GADD45 beta (Growth arrest and DNA-damage-inducible beta) | 4616 | MYD118; GADD45BETA | 34513292.. | Chromatin Remodeler | Unkown | Unkown | |
| GADD45G | Chromatin remodelling | O95257 | GADD45G protein | 10912 | CR6; DDIT2; GRP17; GADD45gamma | 33945602.. | Chromatin Remodeler | Unkown | Unkown | |
| GATAD1 | Histone modification read | Q8WUU5 | GATA zinc finger domain-containing protein 1 | 57798 | Unkown | 31286678 | Histone Modifier | Reader | Unkown | |
| GATAD2A | Histone modification read;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q86YP4 | Transcriptional repressor p66-alpha | 54815 | NuRD;GATA zinc finger domain containing;ATP-dependent chromatin remodelling | 30122475.. | Histone Modifier | Reader | Unkown | |
| GATAD2B | Histone modification read;Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q8WXI9 | Transcriptional repressor p66-beta | 57459 | NuRD;GATA zinc finger domain containing;ATP-dependent chromatin remodelling | 31949314.. | Histone Modifier | Reader | Unkown | |
| GFI1 | Chromatin remodelling | Q99684 | Zinc finger protein Gfi-1 | 2672 | SCN2; GFI-1; GFI1A; ZNF163 | 31289136.. | Chromatin Remodeler | Unkown | Unkown | |
| GLYATL1 | Histone Modification(K27 writer) | Q969I3 | Glycine N-acyltransferase-like protein 1 | 92292 | glycine-N-acyltransferase-like 1 (GNAT) | 34782279.. | Histone Modifier | Writer | Unkown | |
| GLYR1 | Histone modification read | Q49A26 | Putative oxidoreductase GLYR1 | 84656 | PWWP | 23260659.. | Histone Modifier | Reader | Unkown | |
| GSE1 | Histone modification erase(Histone acetylation) | Q14687 | Genetic suppressor element 1 | 23199 | BHC, LSD-CoREST | 34862459.. | Histone Modifier | Eraser | Unkown | |
| GSG2 | Histone modification write(Histone phosphorylation) | Q8TF76 | Non-specific serine/threonine protein kinase (EC 2.7.11.1) | 83903 | Unkown | 32439830.. | Histone Modifier | Writer | Unkown | |
| GTF3C4 | Histone modification write(Histone acetylation) | Q9UKN8 | GTF3C4 protein | 9329 | Unkown | 26153137 | Histone Modifier | Writer | Unkown | |
| HAT1 | Histone modification write(Histone acetylation) | O14929 | Histone acetyltransferase type B catalytic subunit | 8520 | Histone acetyltransferases;HAT | 31278053.. | Histone Modifier | Writer | Unkown | |
| HCFC1 | Chromatin remodelling;Histone Modification(Acetylation, methylation and phosphorylation Reader) | P51610 | HCFC1 protein | 3054 | NSL, COMPASS, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7;host cell factor family | 35013307.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| HCFC2 | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9Y5Z7 | Host cell factor 2 (HCF-2) (C2 factor) | 29915 | MLL-HCF, CHD8, MLL2/3, MLL4/WBP7;host cell factor family | 28970238 | Histone Modifier | Reader,Writer | Unkown | |
| HDAC10 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q969S8 | Polyamine deacetylase HDAC10 (EC 3.5.1.48) (EC 3.5.1.62) (Histone deacetylase 10) (HD10) | 83933 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32540961.. | Histone Modifier | Eraser | Unkown | |
| HDAC11 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q96DB2 | Histone deacetylase 11 | 79885 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32661313.. | Histone Modifier | Eraser | Unkown | |
| HDAC3 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Modulation of cell growth and apoptosis by down-regulation of p53.;Eraser | O15379 | Histone deacetylase 3 | 8841 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32731255.. | Histone Modifier | Eraser | Unkown | |
| HDAC4 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | P56524 | Histone deacetylase (EC 3.5.1.98) | 9759 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 30503143.. | Histone Modifier | Eraser | Unkown | |
| HDAC5 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q9UQL6 | Histone deacetylase (EC 3.5.1.98) | 10014 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32612176.. | Histone Modifier | Eraser | Unkown | |
| HDAC6 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Eraser | Q9UBN7 | Histone deacetylase 6 | 10013 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 12024216.. | Histone Modifier | Eraser | Unkown | |
| HDAC7 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q8WUI4 | Histone deacetylase 7 | 51564 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 29126425.. | Histone Modifier | Eraser | Unkown | |
| HDAC8 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser) | Q9BY41 | Histone deacetylase (EC 3.5.1.98) | 55869 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 32315388.. | Histone Modifier | Eraser | Unkown | |
| HDAC9 | Histone modification erase(Histone acetylation);Histone Modification(K27 eraser);Protects neurons from apoptosis. | Q9UKV0 | Histone deacetylase (EC 3.5.1.98) | 9734 | Histone deacetylase (HDAC);Histone deacetylases;HDAC | 31712770.. | Histone Modifier | Eraser | Unkown | |
| HDGF | Chromatin remodelling, TF( TF repressor) | P51858 | Hepatoma-derived growth factor 4b | 3068 | HMG1L2 | 31582403 | Chromatin Remodeler | Unkown | Unkown | |
| HDGFL2 | Histone modification read | Q7Z4V5 | Hepatoma-derived growth factor-related protein 2 | 84717 | HRP2; HDGF2; HRP-2; HDGF-2; HDGFRP2 | 33477970.. | Histone Modifier | Reader | Unkown | |
| HELLS | Chromatin remodelling;Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | Q9NRZ9 | Lymphoid specific helicase variant1 (Lymphoid-specific helicase) | 3070 | LSH; PASG; SMARCA6; Nbla10143 | 30516846.. | Chromatin Remodeler | Unkown | Unkown | |
| HIF1AN | Histone modification erase cofactor(Histone acetylation) | Q9NWT6 | Hypoxia-inducible factor 1-alpha inhibitor | 55662 | Unkown | 31410089.. | Histone Modifier | Eraser | Unkown | |
| HINFP | Histone modification read, TF, TF( TF activator, TF repressor) | Q9BQA5 | Histone H4 transcription factor | 25988 | Unkown | 34620709.. | Histone Modifier | Reader | Unkown | |
| HIRA | Histone modification read;general repressor | P54198 | Protein HIRA | 7290 | Histone | 32895554.. | Histone Modifier | Reader | Unkown | |
| HIRIP3 | Histone modification read | Q9BW71 | HIRA-interacting protein 3 | 8479 | Unkown | 17391060 | Histone Modifier | Reader | Unkown | |
| HLCS | Histone modification write | P50747 | Biotin--protein ligase | 3141 | Unkown | 34027283.. | Histone Modifier | Writer | Unkown | |
| HLTF | Chromatin remodelling cofactor | Q14527 | HLTF protein | 6596 | ZBU1; HLTF1; RNF80; HIP116; SNF2L3; HIP116A; SMARCA3 | 32442397.. | Chromatin Remodeler | Unkown | Unkown | |
| HMG20A | Chromatin remodelling cofactor | Q9NP66 | High mobility group protein 20A | 10363 | HMGX1; HMGXB1 | 34093866.. | Chromatin Remodeler | Unkown | Unkown | |
| HMG20B | Chromatin remodelling | Q9P0W2 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related | 10362 | SOXL; HMGX2; BRAF25; BRAF35; HMGXB2; PP7706; pp8857; SMARCE1r | 21606163 | Chromatin Remodeler | Unkown | Unkown | |
| HMGB1 | Chromatin remodelling | P09429 | High mobility group box 1 | 3146 | HMG1; HMG3; HMG-1; SBP-1 | 20192808.. | Chromatin Remodeler | Unkown | Unkown | |
| HMGN1 | Chromatin remodelling | P05114 | High-mobility group nucleosome binding domain 1 | 3150 | HMG14 | 29503123 | Chromatin Remodeler | Unkown | Unkown | |
| HMGN2 | Chromatin remodelling | P05204 | Non-histone chromosomal protein HMG-17 | 3151 | HMG17 | 25060707.. | Chromatin Remodeler | Unkown | Unkown | |
| HMGN3 | Chromatin remodelling | Q15651 | High mobility group nucleosome-binding domain-containing protein 3 | 9324 | TRIP7; PNAS-24; PNAS-25 | 35354046 | Chromatin Remodeler | Unkown | Unkown | |
| HMGN4 | Chromatin remodelling | O00479 | High mobility group nucleosome-binding domain-containing protein 4 | 10473 | NHC; HMG17L3 | 35792800 | Chromatin Remodeler | Unkown | Unkown | |
| HMGN5 | Chromatin remodelling | P82970 | High mobility group nucleosome-binding domain-containing protein 5 | 79366 | NSBP1; NBP-45 | 32315283 | Chromatin Remodeler | Unkown | Unkown | |
| HNF1A | Possible regulation of transcription through chromatin remodelling | P20823 | HNF1 alpha B splice variant 3 (HNF1 alpha B splice variant 5) | 6927 | HNF1; LFB1; TCF1; MODY3; TCF-1; HNF-1A; IDDM20 | 30185552 | Chromatin Remodeler | Unkown | Unkown | |
| HP1BP3 | Chromatin remodelling | Q5SSJ5 | Heterochromatin protein 1-binding protein 3 (Protein HP1-BP74) | 50809 | HP1BP74; HP1-BP74 | 27425409.. | Chromatin Remodeler | Unkown | Unkown | |
| HR | Histone modification erase(Histone methylation) | O43593 | Hair growth associated | 55806 | Unkown | 34636192.. | Histone Modifier | Eraser | Unkown | |
| HSPA1A | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation) | P0DMV8 | Heat shock 70 kDa protein 1A | 3303 | CHD8, MLL2/3, MLL4/WBP7 | 34858604.. | Histone Modifier | Writer | Unkown | |
| HUWE1 | Histone modification write(Histone ubiquitination) | Q7TMY8 | Alternative protein HUWE1 | 10075 | Unkown | 33104527.. | Histone Modifier | Writer | Unkown | |
| IDH1 | DNA modification(DNA methylation editor/eraser) | O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | 3417 | Isocitrate dehydrogenase 1 (IDH) | 31637414.. | DNA Methylator | Unkown | Eraser | |
| IDH2 | DNA modification(DNA methylation editor/eraser) | P48735 | Isocitrate dehydrogenase | 3418 | Isocitrate dehydrogenase 2 (IDH) | 19228619.. | DNA Methylator | Unkown | Eraser | |
| IKZF1 | Chromatin remodelling, TF;Targets NuRD/Mi-2 and SWI/SNF complexes in a single complex | Q13422 | DNA-binding protein Ikaros | 10320 | IK1; LYF1; LyF-1; IKAROS; PPP1R92; PRO0758; ZNFN1A1; Hs.54452 | 19129520.. | Chromatin Remodeler | Unkown | Unkown | |
| ING1 | Histone modification read | Q9UK53 | Inhibitor of growth protein 1 | 3621 | Bromo-PHD | 26306560.. | Histone Modifier | Reader | Unkown | |
| ING2 | Histone modification read | Q9H160 | Inhibitor of growth protein | 3622 | mSin3A-like complex;Bromo-PHD | 23412501.. | Histone Modifier | Reader | Unkown | |
| ING3 | Chromatin remodelling, Histone modification write cofactor( Histone acetylation) | Q9NXR8 | Inhibitor of growth protein | 54556 | SWR, NuA4, Piccolo_NuA4;Bromo-PHD | 30804473.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | |
| ING4 | Histone modification read;Facilitates targeting of HBO1-mediated acetylation to H3K4me3 sites. | Q9UNL4 | Inhibitor of growth protein 4 | 51147 | HBO1;Histone acetyltransferases;Bromo-PHD | 30745827.. | Histone Modifier | Reader | Unkown | |
| ING5 | Histone modification read | Q8WYH8 | Inhibitor of growth protein 5 | 84289 | HBO1, MOZ/MORF;Bromo-PHD | 28490335.. | Histone Modifier | Reader | Unkown | |
| INO80 | Chromatin remodelling;Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | Q9ULG1 | Chromatin-remodeling ATPase INO80 | 54617 | INOC1; INO80A; hINO80 | 34242850.. | Chromatin Remodeler | Unkown | Unkown | |
| INO80B | Chromatin remodelling cofactor | Q9C086 | INO80 complex subunit B | 83444 | IES2; hIes2; PAPA-1; ZNHIT4; HMGA1L4; HMGIYL4; PAP-1BP | 25143393 | Chromatin Remodeler | Unkown | Unkown | |
| INO80C | Chromatin remodelling cofactor | Q6PI98 | INO80 complex subunit C | 125476 | IES6; hIes6; C18orf37 | 28735899.. | Chromatin Remodeler | Unkown | Unkown | |
| INO80D | Chromatin remodelling cofactor | Q53TQ3 | Alternative protein INO80D | 54891 | 29750421 | Chromatin Remodeler | Unkown | Unkown | ||
| INO80E | Chromatin remodelling cofactor | Q8NBZ0 | INO80 complex subunit E | 283899 | CCDC95 | 28254775.. | Chromatin Remodeler | Unkown | Unkown | |
| JADE1 | Histone modification write(Histone acetylation) | Q6IE81 | Protein Jade-1 | 79960 | HBO1;Bromo-PHD | 34719765.. | Histone Modifier | Writer | Unkown | |
| JADE2 | Histone modification write(Histone acetylation) | Q9NQC1 | E3 ubiquitin-protein ligase Jade-2 | 23338 | HBO1;Bromo-PHD | 25018020.. | Histone Modifier | Writer | Unkown | |
| JADE3 | Histone modification write(Histone acetylation) | Q92613 | Protein Jade-3 | 9767 | HBO1;Bromo-PHD | 29660380 | Histone Modifier | Writer | Unkown | |
| JAK2 | Histone modification write(Histone phosphorylation) | O60674 | Tyrosine-protein kinase (EC 2.7.10.2) | 3717 | Unkown | 24325359.. | Histone Modifier | Writer | Unkown | |
| JARID2 | Histone modification write cofactor(Histone methylation);Essential role in embryonic development, inhibits PRC2 trimethylation of H3K27. | Protein Jumonji | 3720 | PRC2;Histone demethylases;Jumonji | 33479123.. | Histone Modifier | Writer | Unkown | ||
| JDP2 | Chromatin remodelling, Histone modification erase cofactor( Histone acetylation) | Q8WYK2 | Jun dimerization protein 2 | 122953 | Unkown | 31434880.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| JMJD1C | Histone modification erase(Histone methylation);Histone Modification(protein hydroxylases or histone demethylases);H3K9 HDM. | Q15652 | Probable JmjC domain-containing histone demethylation protein 2C | 221037 | jumonji domain containing;Histone demethylases;Jumonji | 30622285.. | Histone Modifier | Eraser | Unkown | |
| JMJD6 | Histone modification erase(Histone methylation);Histone Modification(protein hydroxylases or histone demethylases);H3R2, H4R3 HDM. Key regulator of haematopoietic differentiation. | Q6NYC1 | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 | 23210 | jumonji domain containing;Histone demethylases;Jumonji | 31346162.. | Histone Modifier | Eraser | Unkown | |
| KANSL1 | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation) | Q7Z3B3 | KAT8 regulatory NSL complex subunit 1 | 284058 | NSL, CHD8, MLL2/3, MLL4/WBP7 | 35177641.. | Histone Modifier | Writer | Unkown | |
| KANSL2 | Histone modification write cofactor(Histone acetylation) | Q9H9L4 | KAT8 regulatory NSL complex subunit 2 | 54934 | NSL | 27406830 | Histone Modifier | Writer | Unkown | |
| KANSL3 | Histone modification write cofactor(Histone acetylation) | Q9P2N6 | KAT8 regulatory NSL complex subunit 3 | 55683 | NSL | 28450392.. | Histone Modifier | Writer | Unkown | |
| KAT2A | Histone modification write(Histone acetylation);Histone Modification(acetylation writer);histone modifiers(acetylation);Writer | Q92830 | Histone acetyltransferase KAT2A | 2648 | TFTC-HAT, SAGA, ATAC, STAGA;Histone acetyltransferases (HAT);Histone acetyltransferases;HAT | 29211711.. | Histone Modifier | Writer | Unkown | |
| KAT2B | Histone modification write(Histone acetylation);Histone Modification(acetylation writer);Writer | Q92831 | Histone acetyltransferase KAT2B | 8850 | Histone acetyltransferases (HAT);Histone acetyltransferases;HAT;HAT | 24051374.. | Histone Modifier | Writer | Unkown | |
| KAT5 | Histone modification write(Histone acetylation);Histone Modification(acetylation writer) | Q92993 | Histone acetyltransferase KAT5 | 10524 | SWR, NuA4, Piccolo_NuA4;Histone acetyltransferases (HAT);Histone acetyltransferases;HAT | 30976101.. | Histone Modifier | Writer | Unkown | |
| KAT6A | Histone modification write(Histone acetylation);Histone Modification(acetylation writer);Component of the MOZ/MORF complex, which has a histone H3 acetyltransferase activity. | Q92794 | Histone acetyltransferase KAT6A | 7994 | MOZ/MORF;Histone acetyltransferases (HAT) KAT6A;Histone acetyltransferases;HAT;HAT | 30069049.. | Histone Modifier | Writer | Unkown | |
| KAT6B | Histone modification write(Histone acetylation);Histone Modification(acetylation writer) | Q8WYB5 | Histone acetyltransferase (EC 2.3.1.48) | 23522 | MOZ/MORF;Histone acetyltransferases (HAT) KAT6B;Histone acetyltransferases;HAT | 32424177.. | Histone Modifier | Writer | Unkown | |
| KAT7 | Histone modification write(Histone acetylation);Histone Modification(acetylation writer);Responsible for the bulk of histone H4 acetylation in vivo.;Writer | O95251 | Histone acetyltransferase (EC 2.3.1.48) | 11143 | HBO1;Histone acetyltransferases (HAT) KAT7;Histone acetyltransferases;HAT | 32164722.. | Histone Modifier | Writer | Unkown | |
| KAT8 | Histone modification write(Histone acetylation);Histone Modification(acetylation writer) | Q9H7Z6 | Histone acetyltransferase (EC 2.3.1.48) | 84148 | NSL, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7;Histone acetyltransferases (HAT) KAT8;Histone acetyltransferases;HAT | 33657400.. | Histone Modifier | Writer | Unkown | |
| KDM1B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));HDM, required for de novo DNA methylation of a subset of imprinted genes during oogenesis. | Q8NB78 | Lysine-specific histone demethylase 1B | 221656 | lysine (K)-specific demethylase (KDM);DNA methyltransferases | 26766590.. | Histone Modifier | Eraser | Unkown | |
| KDM2A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K36me2 HDM. Required to maintain heterochromatic state at centromeres.;Eraser | Q9Y2K7 | Alternative protein KDM2A | 22992 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 33462408.. | Histone Modifier | Eraser | Unkown | |
| KDM2B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3, H3K36me2 HDM. Represses rRNA genes. | Q8NHM5 | Lysine-specific demethylase 2B | 84678 | BCOR;lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji;Jumonji | 31197256.. | Histone Modifier | Eraser | Unkown | |
| KDM3A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me2/me1 HDM. | Q9Y4C1 | Lysine-specific demethylase 3A | 55818 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 31629659.. | Histone Modifier | Eraser | Unkown | |
| KDM3B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9 HDM. | Q7LBC6 | Lysine-specific demethylase 3B | 51780 | lysine (K)-specific demethylase (KDM);Histone demethylases | 30929739.. | Histone Modifier | Eraser | Unkown | |
| KDM4A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3, H3K36me3 HDM.;Eraser | O75164 | Alternative protein KDM4A | 9682 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 32231309.. | Histone Modifier | Eraser | Unkown | |
| KDM4B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3 HDM. | O94953 | Lysine-specific demethylase 4B | 23030 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 33571444.. | Histone Modifier | Eraser | Unkown | |
| KDM4C | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3, H3K36me3 HDM. | Q9H3R0 | Lysine-specific demethylase 4C | 23081 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 32402251.. | Histone Modifier | Eraser | Unkown | |
| KDM4D | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K9me3/me2 HDM. | Q6B0I6 | Lysine-specific demethylase 4D | 55693 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 30060750.. | Histone Modifier | Eraser | Unkown | |
| KDM4E | Histone modification erase(Histone methylation) | B2RXH2 | Lysine-specific demethylase 4E | 390245 | Unkown | 29453221 | Histone Modifier | Eraser | Unkown | |
| KDM5A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me2/me3 HDM. Prominent role in cell differentiation and senescence (17).;Eraser | P29375 | Lysine-specific demethylase 5A | 5927 | lysine (K)-specific demethylase (KDM);Histone demethylases | 33596982.. | Histone Modifier | Eraser | Unkown | |
| KDM5C | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3/me2 HDM. Participates in the repression of neuronal genes.;Eraser | P41229 | [Histone H3]-trimethyl-L-lysine(4) demethylase (EC 1.14.11.67) | 8242 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 31221981.. | Histone Modifier | Eraser | Unkown | |
| KDM5D | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K4me3/me2 HDM. | Q9BY66 | [Histone H3]-trimethyl-L-lysine(4) demethylase (EC 1.14.11.67) | 8284 | lysine (K)-specific demethylase (KDM);Histone demethylases | 29863497.. | Histone Modifier | Eraser | Unkown | |
| KDM6A | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K27me2/me3 HDM. Regulation of HOX gene expression. | O15550 | Lysine-specific demethylase 6A | 7403 | CHD8, MLL2/3, MLL4/WBP7, COMPASS-like MLL3,4;lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 30872525.. | Histone Modifier | Eraser | Unkown | |
| KDM6B | Histone modification erase(Histone methylation);Histone Modification(Histone demethylase (HDM));H3K27me2/me3 HDM. Regulation of HOX gene expression.;Eraser | O15054 | Lysine-specific demethylase 6B | 23135 | lysine (K)-specific demethylase (KDM);Histone demethylases;Jumonji | 32299951.. | Histone Modifier | Eraser | Unkown | |
| KDM7A | Histone modification erase(Histone methylation) | Q6ZMT4 | Lysine-specific demethylase 7A | 80853 | Jumonji | 32935279.. | Histone Modifier | Eraser | Unkown | |
| KDM8 | Histone modification erase(Histone methylation);H3K36me2 HDM. Required for G2/M cell cycle progression. | Q8N371 | Bifunctional peptidase and arginyl-hydroxylase JMJD5 | 79831 | Histone demethylases;Jumonji | 20457893.. | Histone Modifier | Eraser | Unkown | |
| KEAP1 | Chromatin remodelling | Q14145 | Kelch-like ECH-associated protein 1 | 9817 | INrf2; KLHL19 | 29590092.. | Chromatin Remodeler | Unkown | Unkown | |
| KMT2A | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4 HMT. Key regulator of development and haematopoiesis. | Q03164 | Histone-lysine N-methyltransferase 2A | 4297 | MLL-HCF, CHD8, COMPASS-like MLL1,2;lysine (K)-specific methyltransferase (KMT2A);Histone methyltransferases;SET-HMT | 35288693.. | Histone Modifier | Writer | Unkown | |
| KMT2B | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4 HMT. Required to control the bulk of H3K4me3 during oocyte growth and preimplantation. | Q9UMN6 | Histone-lysine N-methyltransferase 2B | 9757 | Menin-associated_HMT, MLL2/3, COMPASS-like MLL3,4;lysine (K)-specific methyltransferase(KMT2B);Histone methyltransferases;SET-HMT | 33150406.. | Histone Modifier | Writer | Unkown | |
| KMT2C | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4 HMT. | Q8NEZ4 | Histone-lysine N-methyltransferase 2C | 58508 | MLL2/3, COMPASS-like MLL3,4;lysine (K)-specific methyltransferase (KMT2C);Histone methyltransferases;SET-HMT | 35449309.. | Histone Modifier | Writer | Unkown | |
| KMT2D | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4 HMT. | O14686 | Histone-lysine N-methyltransferase 2D | 8085 | COMPASS-like MLL1,2, MLL4/WBP7, COMPASS-like MLL3,4;lysine (K)-specific methyltransferase (KMT2D);Histone methyltransferases;SET-HMT | 26366712.. | Histone Modifier | Writer | Unkown | |
| KMT2E | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4me1/me2 HMT. Key regulator of haematopoiesis. | Q8IZD2 | Inactive histone-lysine N-methyltransferase 2E | 55904 | lysine (K)-specific methyltransferase(KMT2E);Histone methyltransferases;SET-HMT | 28069604.. | Histone Modifier | Writer | Unkown | |
| KMT5A | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));Trimethylates H4K20 | Q9NQR1 | N-lysine methyltransferase KMT5A | 387893 | SET domain containing;Histone methyltransferases;SET-HMT | 35449131.. | Histone Modifier | Writer | Unkown | |
| KMT5B | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H4K20me3 HMT. Key in constitutive heterochromatin formation at pericentormeric regions. | Q4FZB7 | [histone H4]-N-methyl-L-lysine20 N-methyltransferase KMT5B (EC 2.1.1.361) (EC 2.1.1.362) ([histone H4]-lysine20 N-methyltransferase KMT5B) | 51111 | suppressor of variegation 4-20 homolog;Histone methyltransferases;SET-HMT | 34876565.. | Histone Modifier | Writer | Unkown | |
| KMT5C | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H4K20me3 HMT. Key in constitutive heterochromatin formation at pericentormeric regions. | Q86Y97 | Histone-lysine N-methyltransferase KMT5C | 84787 | suppressor of variegation 4-20 homolog;Histone methyltransferases;SET-HMT | 35404406.. | Histone Modifier | Writer | Unkown | |
| L3MBTL1 | Histone modification read | Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | 26013 | L3MBTL1;Polycomb Repressive Complex 1;MBT | 17540172.. | Histone Modifier | Reader | Unkown | |
| L3MBTL2 | Histone modification read | Q969R5 | Lethal(3)malignant brain tumor-like protein 2 | 83746 | RING2-L3MBTL2;MBT | 29581593.. | Histone Modifier | Reader | Unkown | |
| L3MBTL3 | Histone modification read | Q96JM7 | Lethal(3)malignant brain tumor-like protein 3 | 84456 | MBT | 29691401.. | Histone Modifier | Reader | Unkown | |
| L3MBTL4 | Histone modification read | Q8NA19 | Lethal(3)malignant brain tumor-like protein 4 | 91133 | MBT | 20698951.. | Histone Modifier | Reader | Unkown | |
| LAS1L | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation) | Q9Y4W2 | Ribosomal biogenesis protein LAS1L | 81887 | CHD8, MLL2/3, MLL4/WBP7 | 35814393 | Histone Modifier | Writer | Unkown | |
| LEO1 | Histone modification write cofactor(Histone ubiquitination) | Q8WVC0 | RNA polymerase-associated protein LEO1 | 123169 | Unkown | 34096589.. | Histone Modifier | Writer | Unkown | |
| LRWD1 | Chromatin remodelling | Q9UFC0 | Leucine-rich repeat and WD repeat-containing protein 1 | 222229 | ORCA; CENP-33 | 27924004 | Chromatin Remodeler | Unkown | Unkown | |
| MAP3K7 | Histone modification write | O43318 | Mitogen-activated protein kinase kinase kinase 7 | 6885 | Unkown | 32592194.. | Histone Modifier | Writer | Unkown | |
| MAPKAPK3 | Chromatin remodelling | Q16644 | Non-specific serine/threonine protein kinase (EC 2.7.11.1) | 7867 | 3PK; MK-3; MAPKAP3; MAPKAP-K3; MAPKAPK-3 | 19208361.. | Chromatin Remodeler | Unkown | Unkown | |
| MASTL | Histone modification write(Histone phosphorylation) | Q96GX5 | Serine/threonine-protein kinase greatwall | 84930 | Unkown | 30068336.. | Histone Modifier | Writer | Unkown | |
| MAX | Histone modification write cofactor, Histone modification write cofactor, TF, TF(Histone methylation, Histone acetylation, TF activator, TF repressor) | P61244 | Protein max (Myc-associated factor X) | 4149 | CHD8, MLL2/3, MLL4/WBP7 | 34882442.. | Histone Modifier | Writer | Unkown | |
| MAZ | Chromatin remodelling | P56270 | Myc-associated zinc finger protein | 4150 | PUR1; ZF87; Pur-1; SAF-1; SAF-2; SAF-3; Zif87; ZNF801 | 35145304.. | Chromatin Remodeler | Unkown | Unkown | |
| MBD1 | Histone modification write cofactor, TF(Histone methylation, TF repressor);DNA modification(DNA methylation reader);Essential for embryonic development. Specifically bind methylated DNA and repress transcription at methylated promoters. | Q9UIS9 | Methyl-CpG-binding domain protein 1 | 4152 | Methyl-CpG-Binding Protein (MBD);DNA methyltransferases;DNMT-MBD | 30849389.. | DNA Methylator,Histone Modifier | Writer | Reader | |
| MBD2 | Histone modification write cofactor, Histone modification erase cofactor, TF(Histone methylation, Histone acetylation, TF repressor);DNA modification(DNA methylation reader);Essential for embryonic development. Also bind methylated DNA. | Q9UBB5 | Methyl-CpG-binding domain protein 2 | 8932 | NuRD, MeCP1;Methyl-CpG-Binding Protein (MBD);ATP-dependent chromatin remodelling;DNMT-MBD | 33277324.. | DNA Methylator,Histone Modifier | Writer,Eraser | Reader | |
| MBD3 | Histone modification erase cofactor(Histone acetylation);DNA modification(DNA methylation reader) | O95983 | Methyl-CpG-binding domain protein 3 | 53615 | NuRD;Methyl-CpG-Binding Protein (MBD);DNMT-MBD | 30122475.. | DNA Methylator,Histone Modifier | Eraser | Reader | |
| MBD4 | DNA modification;DNA modification(DNA methylation reader) | O95243 | Methyl-CpG-binding domain protein 4 | 8930 | Methyl-CpG-Binding Protein (MBD);DNA methyltransferases;DNMT-MBD | 30287469.. | DNA Methylator | Unkown | Reader | |
| MBD5 | Chromatin remodelling | Q9P267 | Methyl-CpG-binding domain protein 5 | 55777 | MRD1 | 34083448.. | Chromatin Remodeler | Unkown | Unkown | |
| MBD6 | Chromatin remodelling | Q96DN6 | Methyl-CpG-binding domain protein 6 | 114785 | 34083448 | Chromatin Remodeler | Unkown | Unkown | ||
| MBIP | Histone modification write cofactor(Histone acetylation) | Q9NS73 | MAP3K12-binding inhibitory protein 1 | 51562 | ATAC | 32963352 | Histone Modifier | Writer | Unkown | |
| MCRS1 | Histone modification write(Histone acetylation) | Q96EZ8 | Microspherule protein 1 | 10445 | Ino80, NSL, CHD8, MLL2/3, MLL4/WBP7 | 25816988.. | Histone Modifier | Writer | Unkown | |
| MDC1 | Histone modification read | Q14676 | Mediator of DNA damage checkpoint 1 (EC 6.3.2.11) | 9656 | Unkown | 30898438.. | Histone Modifier | Reader | Unkown | |
| MEAF6 | Histone modification write cofactor(Histone acetylation) | Q9HAF1 | Chromatin modification-related protein MEAF6 | 64769 | HBO1, NuA4, MOZ/MORF | 24530230.. | Histone Modifier | Writer | Unkown | |
| MECOM | Histone Modification(K9 writer) | Q03112 | Histone-lysine N-methyltransferase MECOM | 2122 | MDS1 and EVI1 complex locus;SET-HMT | 32219447.. | Histone Modifier | Writer | Unkown | |
| MECP2 | Histone modification write cofactor, Histone modification write cofactor, TF(Histone methylation, Histone acetylation, TF repressor);DNA modification(DNA methylation reader) | P51608 | Methyl-CpG-binding protein 2 | 4204 | Methyl-CpG-Binding Protein (MBD);DNA methyltransferases;DNMT-MBD | 31784358.. | DNA Methylator,Histone Modifier | Writer | Reader | |
| MEN1 | Histone modification write cofactor(Histone methylation);H3K4 HMT. Essential component of a MLL/SET1 HMT complex. Represses telomerase expression. Role in TGFB1-mediated inhibition of cell-proliferation. | O00255 | Menin | 4221 | Menin-associated_HMT, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7;Histone methyltransferases | 21252315.. | Histone Modifier | Writer | Unkown | |
| MGA | Histone modification write cofactor, Histone modification write cofactor, TF, TF(Histone methylation, Histone acetylation, TF activator, TF repressor);Histone Modification(Acetylation, methylation and phosphorylation Reader) | O43451 | MAX gene-associated protein | 23269 | RING2-L3MBTL2, CHD8, MLL2/3, MLL4/WBP7;MAX dimerization protein | 33523934.. | Histone Modifier | Reader,Writer | Unkown | |
| MGEA5 | Histone modification write(Histone acetylation) | O60502 | Protein O-GlcNAcase | 10724 | HAT | 30911815 | Histone Modifier | Writer | Unkown | |
| MGMT | DNA modification(DNA methylation editor/eraser) | P16455 | Methylated-DNA--protein-cysteine methyltransferase (EC 2.1.1.63) (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) | 4255 | O-6-methylguanine-DNA methyltransferase | 24912512.. | DNA Methylator | Unkown | Eraser | |
| MINA | Histone modification erase(Histone methylation) | Q81UF8 | Ribosomal oxygenase 2 | 84864 | Unkown | 30728462.. | Histone Modifier | Eraser | Unkown | |
| MLL | Histone-lysine N-methyltransferase MLL | Q03164 | MLL | 4297 | Unkown | 25998713.. | Histone Modifier | Writer | Unkown | |
| MLL2 | Histone-lysine N-methyltransferase MLL2 | O14686 | [Histone H3]-lysine(4) N-methyltransferase (EC 2.1.1.364) | 8085 | Unkown | 27387124.. | Histone Modifier | Writer | Unkown | |
| MLL3 | Histone-lysine N-methyltransferase MLL3 | Q8NEZ4 | MLL3 protein | 58508 | Unkown | 28483418.. | Histone Modifier | Writer | Unkown | |
| MLLT1 | Chromatin remodelling cofactor | Q03111 | Protein ENL | 4298 | ENL; LTG19; YEATS1 | 30288907.. | Chromatin Remodeler | Unkown | Unkown | |
| MLLT10 | Histone modification write cofactor(Histone methylation) | P55197 | Protein AF-10 | 8028 | YEATS | 23673860.. | Histone Modifier | Writer | Unkown | |
| MLLT6 | Histone modification write cofactor(Histone methylation) | P55198 | MLLT6 protein | 4302 | YEATS | 7568208;33063451;35091795 | Histone Modifier | Writer | Unkown | |
| MORF4L1 | Histone modification read;Histone Modification(K36 reader) | Q9Y605 | Mortality factor 4-like protein 1 | 10933 | NuA4;mortality factor 4 like 1;MRG | 21466675.. | Histone Modifier | Reader | Unkown | |
| MORF4L2 | Histone modification erase cofactor(Histone acetylation) | Q15014 | Mortality factor 4-like protein 2 | 9643 | NuA4;MRG | 35900839.. | Histone Modifier | Eraser | Unkown | |
| MPHOSPH8 | Histone modification read | Q99549 | M-phase phosphoprotein 8 | 54737 | Unkown | 27313751 | Histone Modifier | Reader | Unkown | |
| MRGBP | Histone modification write cofactor(Histone acetylation) | Q9NV56 | MRG/MORF4L-binding protein | 55257 | NuA4;MRG;MRG | 30076933.. | Histone Modifier | Writer | Unkown | |
| MSH6 | Histone modification read | P52701 | DNA mismatch repair protein | 2956 | Unkown | 21642682.. | Histone Modifier | Reader | Unkown | |
| MSL1 | Histone modification write(Histone ubiquitination) | Q68DK7 | Male-specific lethal 1 homolog | 339287 | Unkown | 27183194.. | Histone Modifier | Writer | Unkown | |
| MSL2 | Histone modification write(Histone ubiquitination) | Q9HCI7 | E3 ubiquitin-protein ligase MSL2 | 55167 | Unkown | 33208948.. | Histone Modifier | Writer | Unkown | |
| MSL3 | Histone modification read | Q8N5Y2 | Male-specific lethal 3 homolog | 10943 | MRG | 30224647.. | Histone Modifier | Reader | Unkown | |
| MTA1 | Chromatin remodelling cofactor | Q13330 | Metastasis-associated protein MTA1 | 9112 | 31487842 | Chromatin Remodeler | Unkown | Unkown | ||
| MTA2 | Histone modification erase cofactor(Histone acetylation) | O94776 | Metastasis-associated protein MTA2 | 9219 | NuRD;ATP-dependent chromatin remodelling;Bromo-PHD | 24010737.. | Histone Modifier | Eraser | Unkown | |
| MTA3 | Chromatin remodelling cofactor;Maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a HDAC-dependent manner.;Remodeler | Q9BTC8 | Metastasis-associated protein MTA3 | 57504 | Unkown | 31810000 | Chromatin Remodeler | Unkown | Unkown | |
| MTF2 | Polycomb group (PcG) protein;Required for PRC2-mediated Hox repression. | Q9Y483 | Metal-response element-binding transcription factor 2 | 22823 | M96; PCL2; TDRD19A; dJ976O13.2 | 29808031.. | Histone Modifier | Unkown | Unkown | |
| MUM1 | Histone modification read;Opens chromatin to facilitate DNA damage repair | Q2TAK8 | MUM1 protein | 84939 | Other chromatin regulators | 17138820.. | Histone Modifier | Reader | Unkown | |
| MYBBP1A | Chromatin remodelling cofactor | Q9BQG0 | Myb-binding protein 1A | 10514 | P160; PAP2 | 33277249.. | Chromatin Remodeler | Unkown | Unkown | |
| MYO1C | Chromatin remodelling cofactor | O00159 | Unconventional myosin-Ic | 4641 | NMI; MMIb; myr2; MMI-beta | 31097328.. | Chromatin Remodeler | Unkown | Unkown | |
| MYSM1 | Histone modification erase(Histone ubiquitination) | Q5VVJ2 | Deubiquitinase MYSM1 | 114803 | Unkown | 33240758.. | Histone Modifier | Eraser | Unkown | |
| NAA60 | Histone modification write(Histone acetylation) | Q9H7X0 | N-alpha-acetyltransferase 60 (EC 2.3.1.259) (EC 2.3.1.48) (Histone acetyltransferase type B protein 4) (N-acetyltransferase 15) (N-alpha-acetyltransferase F) | 79903 | Unkown | 32548857.. | Histone Modifier | Writer | Unkown | |
| NASP | Chromatin remodelling | P49321 | Nuclear autoantigenic sperm protein (NASP) | 4678 | HMDRA1; FLB7527; PRO1999 | 35489058.. | Chromatin Remodeler | Unkown | Unkown | |
| NAT10 | Histone modification write(Histone acetylation) | Q9H0A0 | RNA cytidine acetyltransferase | 55226 | HAT | 24786082.. | Histone Modifier | Writer | Unkown | |
| NBN | Chromatin remodelling | O60934 | Nibrin | 4683 | ATV; NBS; P95; NBS1; AT-V1; AT-V2 | 28347426.. | Chromatin Remodeler | Unkown | Unkown | |
| NCOA1 | Histone modification write(Histone acetylation);Histone Modification(Histone acetyltransferases) | Q15788 | Nuclear receptor coactivator 1 | 8648 | p160/steroid receptor coactivator (SRC) family;HAT | 29090910.. | Histone Modifier | Writer | Unkown | |
| NCOA2 | Chromatin remodelling cofactor;Histone Modification(Histone acetyltransferases) | Q15596 | Nuclear receptor coactivator 2 | 10499 | SRC2; TIF2; GRIP1; KAT13C; NCoA-2; bHLHe75 | 33574497.. | Histone Modifier,Chromatin Remodeler | Unkown | Unkown | |
| NCOA3 | Histone modification write(Histone acetylation);Histone Modification(Histone acetyltransferases);HAT activity not studied in detail. | Q9Y6Q9 | Nuclear receptor coactivator | 8202 | p160/steroid receptor coactivator (SRC) family;Histone acetyltransferases;HAT | 33766890.. | Histone Modifier | Writer | Unkown | |
| NCOA5 | Histone Modification(Histone acetyltransferases) | Q9HCD5 | Nuclear receptor coactivator 5 | 57727 | CIA; bA465L10.6 | 24332041.. | Histone Modifier | Unkown | Unkown | |
| NCOA6 | Histone modification write cofactor(Histone methylation);Histone Modification(Histone acetyltransferases) | Q14686 | Nuclear receptor coactivator-6 gamma | 23054 | CHD8, MLL2/3, COMPASS-like MLL3,4;p160/steroid receptor coactivator (SRC) family | 21292004.. | Histone Modifier | Writer | Unkown | |
| NCOR1 | Histone modification erase cofactor(Histone acetylation);Forms complex with HDAC1. | O75376 | NCOR1 protein | 9611 | Histone deacetylases | 31529020.. | Histone Modifier | Eraser | Unkown | |
| NCOR2 | Histone modification erase cofactor(Histone acetylation) | Q9Y618 | Nuclear receptor corepressor 2 | 9612 | Unkown | 29262348.. | Histone Modifier | Eraser | Unkown | |
| NEK6 | Histone modification write(Histone phosphorylation) | Q9HC98 | Serine/threonine-protein kinase Nek6 (EC 2.7.11.1) (Never in mitosis A-related kinase 6) (NimA-related protein kinase 6) (Protein kinase SID6-1512) | 10783 | Unkown | 27899381.. | Histone Modifier | Writer | Unkown | |
| NEK9 | Histone modification write(Histone phosphorylation) | Q8TD19 | Alternative protein NEK9 | 91754 | Unkown | 34078910.. | Histone Modifier | Writer | Unkown | |
| NFRKB | Chromatin remodelling cofactor, TF | Q6P4R8 | Nuclear factor-related to kappa-B-binding protein | 4798 | INO80G | 32351584 | Chromatin Remodeler | Unkown | Unkown | |
| NFYB | Chromatin remodelling, TF( TF activator) | P25208 | Nuclear transcription factor Y subunit beta | 4801 | HAP3; CBF-A; CBF-B; NF-YB | 32694663.. | Chromatin Remodeler | Unkown | Unkown | |
| NIPBL | Histone modification erase cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q6KC79 | Nipped-B-like protein | 25836 | Nipped-B homolog | 32409525.. | Histone Modifier | Reader,Eraser | Unkown | |
| NOC2L | Chromatin remodelling, TF( TF repressor) | Q9Y3T9 | Nucleolar complex protein 2 homolog | 26155 | NIR; NET7; NET15; PPP1R112 | 31099044 | Chromatin Remodeler | Unkown | Unkown | |
| NPAS2 | Chromatin remodelling, TF( TF activator) | Q99743 | NPAS2 protein | 4862 | MOP4; PASD4; bHLHe9 | 31765736.. | Chromatin Remodeler | Unkown | Unkown | |
| NSD1 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K36, H4K20 HMT. May influence transcription positively or negatively. | Q96L73 | Histone-lysine N-methyltransferase, H3 lysine-36-specific | 64324 | nuclear receptor binding SET domain protein 1;Histone methyltransferases;SET-HMT | 32929285.. | Histone Modifier | Writer | Unkown | |
| NSD2 | Histone modification write | O96028 | Histone-lysine N-methyltransferase NSD2 | 7468 | WHS; TRX5; KMT3F; KMT3G; MMSET; RAUST; WHSC1; REIIBP | 34555356.. | Histone Modifier | Writer | Unkown | |
| NSD3 | Chromatin remodelling cofactor | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | 54904 | KMT3F; KMT3G; WHISTLE; WHSC1L1; pp14328 | 33536620.. | Chromatin Remodeler | Unkown | Unkown | |
| NSL1 | Histone modification write cofactor(Histone acetylation) | Q96IY1 | Kinetochore-associated protein NSL1 homolog | 25936 | Unkown | 24626182 | Histone Modifier | Writer | Unkown | |
| OGT | Histone modification write(Histone GlcNAcylation) | O15294 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT) | 8473 | NSL | 33592173.. | Histone Modifier | Writer | Unkown | |
| PAF1 | Histone modification write cofactor(Histone ubiquitination) | Q8N7H5 | RNA polymerase II-associated factor 1 homolog | 54623 | Unkown | 28860207.. | Histone Modifier | Writer | Unkown | |
| PAGR1 | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation) | Q9BTK6 | PAXIP1-associated glutamate-rich protein 1 | 79447 | CHD8, MLL2/3, MLL4/WBP7, COMPASS-like MLL3,4 | 32601106 | Histone Modifier | Writer | Unkown | |
| PAK2 | Histone modification write(Histone phosphorylation) | Q13177 | Serine/threonine-protein kinase PAK 2 | 5062 | Unkown | 30620686.. | Histone Modifier | Writer | Unkown | |
| PARG | Chromatin remodelling | Q86W56 | Poly(ADP-ribose) glycohydrolase (EC 3.2.1.143) | 8505 | PARG99 | 35256807.. | Chromatin Remodeler | Unkown | Unkown | |
| PARP1 | Chromatin remodelling | P09874 | Poly [ADP-ribose] polymerase 1 | 142 | PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1 | 28676700.. | Chromatin Remodeler | Unkown | Unkown | |
| PARP2 | Chromatin remodelling cofactor | Q9UGN5 | Poly [ADP-ribose] polymerase (PARP) (EC 2.4.2.-) | 10038 | ARTD2; ADPRT2; PARP-2; ADPRTL2; ADPRTL3; pADPRT-2 | 32939087.. | Chromatin Remodeler | Unkown | Unkown | |
| PAXIP1 | Histone modification write cofactor(Histone methylation) | Q9BTK6 | PAX-interacting protein 1 (PAX transactivation activation domain-interacting protein) | 22976 | CHD8, MLL2/3, MLL4/WBP7, COMPASS-like MLL3,4;BRCT | 23197109.. | Histone Modifier | Writer | Unkown | |
| PBK | Histone modification write(Histone phosphorylation) | Q96KB5 | Lymphokine-activated killer T-cell-originated protein kinase | 55872 | Unkown | 33821572.. | Histone Modifier | Writer | Unkown | |
| PBRM1 | Histone modification read;Regulator of cell proliferation | Q86U86 | Protein polybromo-1 | 55193 | PBAF, SWI/SNF BRM-BRG1;ATP-dependent chromatin remodelling;Bromo-PHD | 32358509.. | Histone Modifier | Reader | Unkown | |
| PCGF6 | Polycomb group (PcG) protein | Q9BYE7 | Polycomb group RING finger protein 6 | 84108 | MBLR; RNF134 | 35933409.. | Histone Modifier | Unkown | Unkown | |
| PCNA | Chromatin remodelling;DNA modification(DNA methylation reader) | P12004 | Proliferating cell nuclear antigen | 5111 | proliferating cell nuclear antigen | 32123106.. | DNA Methylator,Chromatin Remodeler | Unkown | Reader | |
| PDP1 | Histone modification read | Q9P0J1 | [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial | 54704 | Unkown | 12581523.. | Histone Modifier | Reader | Unkown | |
| PELP1 | Histone modification read, Histone modification write cofactor(Histone methylation, Histone acetylation) | Q8IZL8 | Proline-, glutamic acid- and leucine-rich protein 1 | 27043 | CHD8, MLL2/3, MLL4/WBP7 | 34103681.. | Histone Modifier | Reader,Writer | Unkown | |
| PHF10 | Chromatin remodelling;Required for the proliferation of neural progenitors | Q8WUB8 | PHD finger protein 10 (PHF10 isoform Sl) | 55274 | BAF45A; XAP135 | 34465901 | Chromatin Remodeler | Unkown | Unkown | |
| PHF12 | Histone modification erase cofactor(Histone acetylation) | Q96QT6 | PHD finger protein 12 | 57649 | Bromo-PHD | 27956701.. | Histone Modifier | Eraser | Unkown | |
| PHF13 | Histone modification read | Q86YI8 | PHD finger protein 13 (Survival time-associated PHD finger protein in ovarian cancer 1) (SPOC1) | 148479 | Bromo-PHD;Bromo-PHD | 35597793.. | Histone Modifier | Reader | Unkown | |
| PHF14 | Histone modification read | O94880 | PHD finger protein 14 (cDNA FLJ61230, highly similar to PHD finger protein 14) | 9678 | Bromo-PHD | 34365506.. | Histone Modifier | Reader | Unkown | |
| PHF19 | Chromatin remodelling, Histone modification write cofactor( Histone acetylation);Mediates interaction of PRC2 with H3K36me3, essential for full PRC2 activity. | Q5T6S3 | PHD finger protein 19 | 26147 | PRC2;Polycomb Repressive Complex 2;Polycomb group;Polycomb group | 31383640.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | |
| PHF2 | Histone modification erase(Histone methylation);Histone Modification(K4 reader);H3K9me2 HDM. | O75151 | Lysine-specific demethylase PHF2 | 5253 | PHD finger protein;Histone demethylases;Jumonji;Jumonji | 32232336.. | Histone Modifier | Eraser | Unkown | |
| PHF20 | Histone modification write(Histone acetylation) | Q9BVI0 | PHD finger protein 20 | 51230 | NSL, CHD8, MLL2/3, MLL4/WBP7;Bromo-PHD | 23797602.. | Histone Modifier | Writer | Unkown | |
| PHF20L1 | Histone modification read | A8MW92 | PHD finger protein 20-like protein 1 | 51105 | Unkown | 32494608.. | Histone Modifier | Reader | Unkown | |
| PHF21A | Histone modification erase cofactor(Histone methylation) | Q96BD5 | PHD finger protein 21A | 51317 | BHC, LSD-CoREST;Bromo-PHD | 22770980.. | Histone Modifier | Eraser | Unkown | |
| PHF6 | Histone Modification(K4 reader) | Q8IWS0 | PHD finger protein 6 | 84295 | PHD finger protein;Bromo-PHD | 30917958.. | Histone Modifier | Reader | Unkown | |
| PHF8 | Histone modification erase(Histone methylation);Histone Modification(K4 reader);H3K9me1/me2, H3K27me2, H4K20me1 HDM. Key role in cell cycle progression.;Eraser | Q9UPP1 | Histone lysine demethylase PHF8 | 23133 | PHD finger protein;Histone demethylases;Jumonji;Jumonji | 33010150.. | Histone Modifier | Reader,Eraser | Unkown | |
| PHIP | Histone modification read | Q8WWQ0 | PH-interacting protein | 55023 | Bromo-PHD | 30190553.. | Histone Modifier | Reader | Unkown | |
| PIWIL4 | Chromatin remodelling, Histone modification erase cofactor( Histone methylation) | Q7Z3Z4 | Piwi-like protein 4 | 143689 | Unkown | 35609598.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| PKM | Histone modification write cofactor(Histone phosphorylation) | P14618 | Pyruvate kinase (EC 2.7.1.40) | 5315 | Unkown | 34921016.. | Histone Modifier | Writer | Unkown | |
| PKN1 | Histone modification write(Histone phosphorylation) | Q16512 | Serine/threonine-protein kinase N1 | 5585 | Unkown | 34589290.. | Histone Modifier | Writer | Unkown | |
| POGZ | Histone modification read(Histone methylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q7Z3K3 | Pogo transposable element with ZNF domain | 23126 | pogo transposable element with ZNF domain | 32103003.. | Histone Modifier | Reader | Unkown | |
| PPM1G | Chromatin remodelling | O15355 | PPM1G protein | 5496 | PP2CG; PPP2CG; PP2CGAMMA | 33219031.. | Chromatin Remodeler | Unkown | Unkown | |
| PPP2CA | Histone modification write(Histone phosphorylation) | P67775 | Serine/threonine-protein phosphatase (EC 3.1.3.16) | 5515 | Unkown | 30296597.. | Histone Modifier | Writer | Unkown | |
| PPP4C | Histone modification erase(Histone phosphorylation) | P60510 | Serine/threonine-protein phosphatase (EC 3.1.3.16) | 5531 | PPP4C-PPP4R2-PPP4R3A | 35546066.. | Histone Modifier | Eraser | Unkown | |
| PPP4R3A | Histone modification erase cofactor(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q6IN85 | Serine/threonine-protein phosphatase 4 regulatory subunit 3A | 55671 | PPP4C-PPP4R2-PPP4R3A;SMEK homolog | 29130521.. | Histone Modifier | Eraser | Unkown | |
| PPP4R3B | Histone modification erase cofactor(Histone phosphorylation);Histone Modification(Phosphorylation editor) | Q5MIZ7 | Serine/threonine-protein phosphatase 4 regulatory subunit 3B | 57223 | SMEK homolog | 20876121.. | Histone Modifier | Eraser | Unkown | |
| PRDM1 | Histone modification write cofactor(Histone methylation);Histone Modification(Histone methyltransferases) | O75626 | PR domain zinc finger protein 1 (EC 2.1.1.-) | 639 | PR domain containing;SET-HMT | 34861037.. | Histone Modifier | Writer | Unkown | |
| PRDM10 | Histone Modification(Histone methyltransferases) | Q9NQV6 | PR domain zinc finger protein 10 (PR domain-containing protein 10) | 56980 | PFM7 | 32681107.. | Histone Modifier | Unkown | Unkown | |
| PRDM11 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9NQV5 | PR domain-containing protein 11 | 56981 | PR domain containing;SET-HMT | 25499759.. | Histone Modifier | Writer | Unkown | |
| PRDM12 | Histone modification write cofactor(Histone methylation);Histone Modification(Histone methyltransferases) | Q9H4Q4 | PR domain zinc finger protein 12 (EC 2.1.1.-) (PR domain-containing protein 12) | 59335 | PR domain containing;SET-HMT | 32828702.. | Histone Modifier | Writer | Unkown | |
| PRDM13 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9H4Q3 | PR domain zinc finger protein 13 | 59336 | PR domain containing;SET-HMT | 34730112.. | Histone Modifier | Writer | Unkown | |
| PRDM14 | DNA modification(DNA demethylation);Histone Modification(Histone methyltransferases) | Q9GZV8 | PR domain-containing 14 | 63978 | PR domain containing;SET-HMT | 24811060.. | DNA Methylator,Histone Modifier | Unkown | Eraser | |
| PRDM15 | Histone Modification(Histone methyltransferases) | P57071 | PR domain zinc finger protein 15 | 63977 | PFM15; ZNF298; C21orf83 | 28740264.. | Histone Modifier | Unkown | Unkown | |
| PRDM16 | Histone modification write cofactor, TF(Histone methylation, TF repressor);Histone Modification(Histone methyltransferases) | Q9HAZ2 | Alternative protein PRDM16 | 63976 | PR domain containing;SET-HMT | 18719582.. | Histone Modifier | Writer | Unkown | |
| PRDM2 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases);H3K9 HMT | Q13029 | PR domain zinc finger protein 2 | 7799 | PR domain containing;Histone methyltransferases;SET-HMT | 29883756.. | Histone Modifier | Writer | Unkown | |
| PRDM4 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9UKN5 | PR domain zinc finger protein 4 | 11108 | PR domain containing;SET-HMT | 27159578.. | Histone Modifier | Writer | Unkown | |
| PRDM5 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9NQX1 | Alternative protein PRDM5 | 11107 | PR domain containing;SET-HMT | 23873026.. | Histone Modifier | Writer | Unkown | |
| PRDM6 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9NQX0 | Putative histone-lysine N-methyltransferase PRDM6 | 93166 | PR domain containing;SET-HMT | 27181681.. | Histone Modifier | Writer | Unkown | |
| PRDM7 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9NQW5 | Histone-lysine N-methyltransferase PRDM7 | 11105 | PR domain containing;SET-HMT | 27129774.. | Histone Modifier | Writer | Unkown | |
| PRDM8 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9NQV8 | PRDM8 protein | 56978 | PR domain containing;SET-HMT | 22284184.. | Histone Modifier | Writer | Unkown | |
| PRDM9 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases);H3K4me3 HMT. Essential for meiotic progression | Q9NQV7 | PR domain zinc finger protein 9 (EC 2.1.1.43) | 56979 | PR domain containing;Histone methyltransferases;SET-HMT | 33097538.. | Histone Modifier | Writer | Unkown | |
| PRKAA1 | Histone modification write(Histone phosphorylation) | Q13131 | 5'-AMP-activated protein kinase catalytic subunit alpha-1 | 5562 | Unkown | 30405100.. | Histone Modifier | Writer | Unkown | |
| PRKAA2 | Histone modification write(Histone phosphorylation) | O95278 | 5'-AMP-activated protein kinase catalytic subunit alpha-2 (EC 2.7.11.1) (EC 2.7.11.27) (EC 2.7.11.31) (Acetyl-CoA carboxylase kinase) (Hydroxymethylglutaryl-CoA reductase kinase) | 5563 | Unkown | 35075806.. | Histone Modifier | Writer | Unkown | |
| PRKAB1 | Histone modification write cofactor(Histone phosphorylation) | Q9Y478 | 5'-AMP-activated protein kinase subunit beta-1 | 5564 | Unkown | 16505254 | Histone Modifier | Writer | Unkown | |
| PRKAB2 | Histone modification write cofactor(Histone phosphorylation) | O43741 | 5'-AMP-activated protein kinase subunit beta-2 (AMPK subunit beta-2) | 5565 | Unkown | 16505254 | Histone Modifier | Writer | Unkown | |
| PRKAG1 | Histone modification write cofactor(Histone phosphorylation) | P54619 | 5'-AMP-activated protein kinase subunit gamma-1 | 5571 | Unkown | 25267969 | Histone Modifier | Writer | Unkown | |
| PRKAG2 | Histone modification write cofactor(Histone phosphorylation) | Q9UGJ0 | 5'-AMP-activated protein kinase subunit gamma-2 | 51422 | Unkown | 25267969 | Histone Modifier | Writer | Unkown | |
| PRKAG3 | Histone modification write cofactor(Histone phosphorylation) | Q9UGI9 | 5'-AMP-activated protein kinase subunit gamma-3 (cDNA FLJ60036, highly similar to 5'-AMP-activated protein kinase subunit gamma-3) | 53632 | Unkown | 22762995.. | Histone Modifier | Writer | Unkown | |
| PRKCA | Histone modification write cofactor(Histone phosphorylation) | Q9NRD5 | PRKCA protein | 5578 | Unkown | 29915258.. | Histone Modifier | Writer | Unkown | |
| PRKCB | Histone modification write(Histone methylation) | P05771 | Protein kinase C beta type | 5579 | Unkown | 31757376.. | Histone Modifier | Writer | Unkown | |
| PRKDC | Histone modification write(Histone phosphorylation) | P78527 | DNA-dependent protein kinase catalytic subunit | 5591 | Unkown | 32238472.. | Histone Modifier | Writer | Unkown | |
| PRMT1 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q99873 | Protein arginine N-methyltransferase 1 | 3276 | protein arginine N-methyltransferase(PRMT);PRMT | 31217189.. | Histone Modifier | Writer | Unkown | |
| PRMT2 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | P55345 | PRMT2 protein | 3275 | protein arginine N-methyltransferase(PRMT);PRMT | 30382083.. | Histone Modifier | Writer | Unkown | |
| PRMT5 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | O14744 | Protein arginine N-methyltransferase 5 | 10419 | methylosome;protein arginine N-methyltransferase(PRMT);PRMT | 33450196.. | Histone Modifier | Writer | Unkown | |
| PRMT6 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q96LA8 | Protein arginine N-methyltransferase 6 | 55170 | protein arginine N-methyltransferase(PRMT);PRMT | 31154022.. | Histone Modifier | Writer | Unkown | |
| PRMT7 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9NVM4 | Protein arginine N-methyltransferase (EC 2.1.1.321) | 54496 | protein arginine N-methyltransferase(PRMT);PRMT | 34171297.. | Histone Modifier | Writer | Unkown | |
| PRMT8 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q9NR22 | Arginine methyltransferase 8 isoform 4 | 56341 | protein arginine N-methyltransferase(PRMT);PRMT | 32521269.. | Histone Modifier | Writer | Unkown | |
| PRMT9 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases) | Q6P2P2 | Protein arginine N-methyltransferase 9 | 90826 | protein arginine N-methyltransferase(PRMT);PRMT;PRMT | 36028484.. | Histone Modifier | Writer | Unkown | |
| PRPF31 | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation) | Q8WWY3 | U4/U6 small nuclear ribonucleoprotein Prp31 | 26121 | CHD8, MLL2/3, MLL4/WBP7 | 33476374.. | Histone Modifier | Writer | Unkown | |
| PRR14 | Histone modification write(Histone phosphorylation) | Q9BWN1 | PRR14 protein | 78994 | Unkown | 32541902.. | Histone Modifier | Writer | Unkown | |
| PSIP1 | Chromatin remodelling | O75475 | PC4 and SFRS1-interacting protein | 11168 | p52; p75; PAIP; DFS70; LEDGF; PSIP2 | 25056311 | Chromatin Remodeler | Unkown | Unkown | |
| PYGO2 | histone binding | Q9BRQ0 | Pygopus homolog 2 | 90780 | 1190004M21Rik | 32727463.. | Histone Modifier | Unkown | Unkown | |
| RAD51 | Histone modification erase(Histone ubiquitination) | Q06609 | DNA repair protein RAD51 homolog 1 | 5888 | BRCC | 28976962.. | Histone Modifier | Eraser | Unkown | |
| RAD54B | Chromatin remodelling | Q9Y620 | DNA repair and recombination protein RAD54B (EC 3.6.4.-) (RAD54 homolog B) | 25788 | RDH54 | 25384516.. | Chromatin Remodeler | Unkown | Unkown | |
| RAD54L | Chromatin remodelling;Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | Q92698 | DNA repair and recombination protein RAD54-like | 8438 | HR54; hHR54; RAD54A; hRAD54 | 25965574.. | Chromatin Remodeler | Unkown | Unkown | |
| RAD54L2 | Chromatin remodelling | Q9Y4B4 | Helicase ARIP4 | 23132 | ARIP4; HSPC325; SRISNF2L | 35061896 | Chromatin Remodeler | Unkown | Unkown | |
| RAG1 | Histone modification write(Histone ubiquitination) | P15918 | V(D)J recombination-activating protein 1 (EC 2.3.2.27) (EC 3.1.-.-) | 5896 | Unkown | 34402853.. | Histone Modifier | Writer | Unkown | |
| RAG2 | Histone modification read;Histone Modification(K4 reader);Reader | P55895 | V(D)J recombination-activating protein 2 | 5897 | recombination activating gene 2 | 34644584.. | Histone Modifier | Reader | Unkown | |
| RAI1 | Chromatin remodelling | Q7Z5J4 | Retinoic acid-induced protein 1 | 10743 | SMS; SMCR | 32374864.. | Chromatin Remodeler | Unkown | Unkown | |
| RARA | Histone modification write cofactor, TF, TF(Histone methylation, TF activator, TF repressor) | P10276 | RARA protein | 5914 | Unkown | 34432867.. | Histone Modifier | Writer | Unkown | |
| RB1 | Chromatin remodelling, Histone modification write( Histone ubiquitination) | P06400 | Retinoblastoma-associated protein | 5925 | CREST-BRG1, L3MBTL1 | 28059767.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | |
| RBBP4 | Histone chaperone;Also part of PRC2 complex. | Q09028 | Histone-binding protein RBBP4 | 5928 | NURF55; RBAP48; lin-53 | 34086947.. | Histone Modifier | Unkown | Unkown | |
| RBBP5 | Histone modification write cofactor(Histone methylation);Complex with MLL | Q15291 | Retinoblastoma-binding protein 5 | 5929 | COMPASS, Menin-associated_HMT, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7, COMPASS-like MLL3,4;Histone methyltransferases;NAP | 31485071.. | Histone Modifier | Writer | Unkown | |
| RBX1 | Histone modification write cofactor(Histone ubiquitination) | P62877 | E3 ubiquitin-protein ligase RBX1 | 9978 | RING finger | 11961546.. | Histone Modifier | Writer | Unkown | |
| RCC1 | Chromatin remodelling | P18754 | Regulator of chromosome condensation 1 isoform 2 | 1104 | CHC1; RCC1-I; SNHG3-RCC1 | 33539787.. | Chromatin Remodeler | Unkown | Unkown | |
| RCOR1 | Histone modification erase cofactor, Histone modification erase cofactor(Histone acetylation, Histone methylation) | Q9UKL0 | Alternative protein RCOR1 | 23186 | BHC, SCL, LSD-CoREST;SANT domain | 24652990.. | Histone Modifier | Eraser | Unkown | |
| RCOR3 | Histone modification erase cofactor(Histone acetylation) | Q9P2K3 | REST corepressor 3 | 55758 | LSD-CoREST;SANT domain | 21258344.. | Histone Modifier | Eraser | Unkown | |
| RERE | Histone lysine demethylase PHF8 | Q9P2R6 | Arginine-glutamic acid dipeptide repeats protein | 473 | Unkown | 20164929 | Histone Modifier | Eraser | Unkown | |
| REST | Histone modification erase cofactor, TF, TF(Histone acetylation, TF activator, TF repressor) | Q13127 | RE1-silencing transcription factor variant E1c/E2g/E3/E4 | 5978 | Unkown | 34625348.. | Histone Modifier | Eraser | Unkown | |
| RING1 | Histone modification write, Polycomb group (PcG) protein(Histone ubiquitination);H2AK119ub. | Q06587 | E3 ubiquitin-protein ligase RING1 | 6015 | PRC1, BCOR, RING2-L3MBTL2, RING2-FBRS;Polycomb Repressive Complex 1 | 33177537.. | Histone Modifier | Writer | Unkown | |
| RIOX2 | Histone modification erase | Q8IUF8 | Bifunctional lysine-specific demethylase and histidyl-hydroxylase (EC 1.14.11.-) | 84864 | ROX; MDIG; MINA; NO52; JMJD10; MINA53 | 34855761.. | Histone Modifier | Eraser | Unkown | |
| RLIM | Histone modification erase cofactor(Histone acetylation) | Q9NVW2 | E3 ubiquitin-protein ligase RLIM | 51132 | Unkown | 33328571.. | Histone Modifier | Eraser | Unkown | |
| RNF168 | Histone modification write(Histone ubiquitination) | Q8IYW5 | E3 ubiquitin-protein ligase RNF168 | 165918 | Unkown | 29403037.. | Histone Modifier | Writer | Unkown | |
| RNF2 | Histone modification write(Histone ubiquitination);H2AK119ub. Acts as the main ub ligase in PRC1. | Q99496 | E3 ubiquitin-protein ligase RING2 (EC 2.3.2.27) (RING finger protein 1B) (RING finger protein 2) (RING-type E3 ubiquitin transferase RING2) | 6045 | PRC1, BCOR, RING2-L3MBTL2, RING2-FBRS, CHD8, MLL2/3, MLL4/WBP7;Polycomb Repressive Complex 1;Polycomb group | 35121885.. | Histone Modifier | Writer | Unkown | |
| RNF20 | Histone modification write(Histone ubiquitination);ubiquitination | Q5VTR2 | E3 ubiquitin protein ligase (EC 2.3.2.27) | 56254 | RING finger;RING finger | 30649429.. | Histone Modifier | Writer | Unkown | |
| RNF40 | Histone modification write cofactor(Histone ubiquitination) | O75150 | E3 ubiquitin protein ligase (EC 2.3.2.27) | 9810 | RING finger;RING finger | 28209164.. | Histone Modifier | Writer | Unkown | |
| RNF8 | Histone modification write(Histone ubiquitination) | O76064 | Alternative protein RNF8 | 9025 | Unkown | 29097665.. | Histone Modifier | Writer | Unkown | |
| RPS6KA3 | Histone modification write cofactor(Histone phosphorylation) | P51812 | RPS6KA3 protein | 6197 | Kinases | 10319851 | Histone Modifier | Writer | Unkown | |
| RPS6KA4 | Histone modification write(Histone phosphorylation) | O75676 | Non-specific serine/threonine protein kinase (EC 2.7.11.1) | 8986 | Kinases | 23599020 | Histone Modifier | Writer | Unkown | |
| RPS6KA5 | Histone modification write(Histone phosphorylation) | O75582 | Ribosomal protein S6 kinase alpha-5 | 9252 | Kinases | 35986314 | Histone Modifier | Writer | Unkown | |
| RSF1 | Histone modification read | Q96T23 | Remodeling and spacing factor 1 | 51773 | RSF;ATP-dependent chromatin remodelling;Bromo-PHD | 34850117.. | Histone Modifier | Reader | Unkown | |
| RUVBL1 | Chromatin remodelling, Histone modification write( Histone phosphorylation) | A7MBG8 | RuvB-like helicase (EC 3.6.4.12) | 8607 | Ino80, SWR, NuA4, NuA4-related complex, CHD8, MLL2/3, MLL4/WBP7, SRCAP;poly (ADP-ribose) polymerase and other nucleotide enzymes | 31665067.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | |
| RUVBL2 | Chromatin remodelling cofactor | Q9Y230 | RuvB-like 2 | 10856 | RVB2; TIH2; ECP51; TIP48; CGI-46; INO80J; REPTIN; TIP49B | 32376767.. | Chromatin Remodeler | Unkown | Unkown | |
| SAFB | Chromatin remodelling | Q15424 | Scaffold attachment factor B1 | 6294 | HAP; HET; SAFB1; SAF-B1 | 31677973.. | Chromatin Remodeler | Unkown | Unkown | |
| SAP130 | Histone modification erase cofactor(Histone acetylation) | Q9H0E3 | Histone deacetylase complex subunit SAP130 | 79595 | Unkown | 34556635.. | Histone Modifier | Eraser | Unkown | |
| SAP18 | Histone modification erase cofactor(Histone acetylation) | O00422 | Histone deacetylase complex subunit SAP18 | 10284 | mSin3A | 9150135;30670829 | Histone Modifier | Eraser | Unkown | |
| SAP25 | Histone modification erase cofactor(Histone acetylation) | Q8TEE9 | Histone deacetylase complex subunit SAP25 | 100316904 | Unkown | 16449650 | Histone Modifier | Eraser | Unkown | |
| SAP30 | Histone modification erase cofactor(Histone acetylation) | O75446 | Histone deacetylase complex subunit SAP30 (30 kDa Sin3-associated polypeptide) (Sin3 corepressor complex subunit SAP30) (Sin3-associated polypeptide p30) | 8819 | mSin3A, mSin3A-like complex | 32820380 | Histone Modifier | Eraser | Unkown | |
| SAP30L | Histone modification erase cofactor(Histone acetylation) | Q9HAJ7 | Histone deacetylase complex subunit SAP30L | 79685 | Unkown | 30820959 | Histone Modifier | Eraser | Unkown | |
| SATB1 | Chromatin remodelling cofactor | Q01826 | DNA-binding protein SATB1 | 6304 | 32669713.. | Chromatin Remodeler | Unkown | Unkown | ||
| SATB2 | Chromatin remodelling cofactor | Q9UPW6 | DNA-binding protein SATB (Special AT-rich sequence-binding protein) | 23314 | GLSS | 31492160.. | Chromatin Remodeler | Unkown | Unkown | |
| SCML2 | Polycomb group (PcG) protein | Q9UQR0 | Sex comb on midleg-like protein 2 (cDNA FLJ60333, highly similar to Sex comb on midleg-like protein 2) | 10389 | Unkown | 25703348.. | Histone Modifier | Unkown | Unkown | |
| SENP1 | Histone modification erase cofactor(Histone sumoylation) | Q9P0U3 | Sentrin-specific protease 1 (EC 3.4.22.-) (Sentrin/SUMO-specific protease SENP1) | 29843 | Unkown | 28258134.. | Histone Modifier | Eraser | Unkown | |
| SENP3 | Histone modification erase, Histone modification write cofactor(Histone sumoylation, Histone acetylation) | Q9H4L4 | Sentrin-specific protease 3 | 26168 | CHD8, MLL2/3, MLL4/WBP7 | 32351703.. | Histone Modifier | Writer,Eraser | Unkown | |
| SETD1A | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));methylation;H3K4 HMT | O15047 | Histone-lysine N-methyltransferase SETD1A | 9739 | COMPASS;SET domain containing;Histone methyltransferases;SET-HMT | 29474905.. | Histone Modifier | Writer | Unkown | |
| SETD1B | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4 HMT. | Q9UPS6 | Histone-lysine N-methyltransferase SETD1B | 23067 | COMPASS;SET domain containing;Histone methyltransferases;SET-HMT | 28381543.. | Histone Modifier | Writer | Unkown | |
| SETD2 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K36 HMT. | Q9BYW2 | Histone-lysine N-methyltransferase SETD2 | 29072 | SET domain containing;Histone methyltransferases;SET-HMT | 32619406.. | Histone Modifier | Writer | Unkown | |
| SETD3 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT)) | Q86TU7 | Actin-histidine N-methyltransferase | 84193 | SET domain containing;SET-HMT | 30626964.. | Histone Modifier | Writer | Unkown | |
| SETD5 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT)) | Q9C0A6 | Histone-lysine N-methyltransferase SETD5 | 55209 | SET domain containing;SET-HMT | 32442403.. | Histone Modifier | Writer | Unkown | |
| SETD6 | Chromatin remodelling, Histone modification write( Histone methylation);Histone Modification(Histone methyltransferases(HMT)) | Q8TBK2 | N-lysine methyltransferase SETD6 (SET domain-containing protein 6) | 79918 | SET domain containing;SET-HMT | 34039605.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | |
| SETD7 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4 HMT | Q8WTS6 | [Histone H3]-lysine(4) N-methyltransferase (EC 2.1.1.364) | 80854 | SET domain containing;Histone methyltransferases;SET-HMT | 34215303.. | Histone Modifier | Writer | Unkown | |
| SETDB1 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K9 HMT.;Writer | Q15047 | Histone-lysine N-methyltransferase SETDB1 | 9869 | SET domain containing;Histone methyltransferases;SET-HMT | 33953401.. | Histone Modifier | Writer | Unkown | |
| SETDB2 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K9 HMT. | Q96T68 | Histone-lysine N-methyltransferase SETDB2 | 83852 | SET domain containing;Histone methyltransferases;SET-HMT | 31350176.. | Histone Modifier | Writer | Unkown | |
| SETMAR | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT)) | Q53H47 | Histone-lysine N-methyltransferase SETMAR (SET domain and mariner transposase fusion protein) (Metnase) [Includes: Histone-lysine N-methyltransferase (EC 2.1.1.357); Transposon Hsmar1 transposase (EC 3.1.-.-)] | 6419 | SET domain containing;SET-HMT | 30329085.. | Histone Modifier | Writer | Unkown | |
| SFMBT2 | Histone modification read, Polycomb group (PcG) protein, TF( TF repressor) | Q5VUG0 | Scm-like with four MBT domains protein 2 | 57713 | MBT | 32971847.. | Histone Modifier | Reader | Unkown | |
| SFPQ | Chromatin remodelling cofactor, RNA modification, TF( TF repressor) | P23246 | Splicing factor, proline- and glutamine-rich | 6421 | PSF; POMP100; PPP1R140 | 32034402.. | Chromatin Remodeler | Unkown | Unkown | |
| SGF29 | Histone modification read | Q96ES7 | SAGA-associated factor 29 | 112869 | ATAC | 33721015.. | Histone Modifier | Reader | Unkown | |
| SHPRH | Histone modification write cofactor(Histone ubiquitination) | Q149N8 | E3 ubiquitin-protein ligase SHPRH | 257218 | SNF2-5 | 31526596.. | Histone Modifier | Writer | Unkown | |
| SIN3A | Histone modification erase cofactor, TF, TF(Histone acetylation, TF activator, TF repressor) | Q96ST3 | Paired amphipathic helix protein Sin3a | 25942 | SWI/SNF_Brg1(I), SWI/SNF_Brm, mSin3A, mSin3A-like complex;HDAC | 34078089.. | Histone Modifier | Eraser | Unkown | |
| SIN3B | Histone modification erase cofactor, TF(Histone acetylation, TF repressor) | Q62141 | Paired amphipathic helix protein Sin3b | 23309 | mSin3A;HDAC | 28807943.. | Histone Modifier | Eraser | Unkown | |
| SIRT1 | Histone modification erase, Histone modification write cofactor(Histone acetylation, Histone methylation);Histone Modification(acetylation editor);Interacts with PRC2, non-histone deacetylase activity. Involved in normal ageing through resistance to cellular stress. Deacetylates p53. Located in nucleus and cytoplasm;Eraser | Q96EB6 | NAD-dependent protein deacetylase sirtuin-1 | 23411 | eNoSc;sirtuin family;Histone deacetylases;HDAC | 28701484.. | Histone Modifier | Writer,Eraser | Unkown | |
| SIRT2 | Histone modification erase, Histone modification write cofactor(Histone acetylation, Histone methylation);Histone Modification(acetylation editor);Deacetylates alpha-tubulin. Located in the cytoplasm | Q8IXJ6 | NAD-dependent protein deacetylase sirtuin-2 | 22933 | sirtuin family;Histone deacetylases;HDAC | 32768387.. | Histone Modifier | Writer,Eraser | Unkown | |
| SIRT6 | Histone modification erase(Histone acetylation);Histone Modification(acetylation editor);Located in the nucleus. H3K9 and H3K56 deacetylase activity.;Eraser | Q8N6T7 | NAD-dependent protein deacetylase sirtuin-6 | 51548 | sirtuin family;Histone deacetylases;HDAC | 31437090.. | Histone Modifier | Eraser | Unkown | |
| SIRT7 | Histone modification erase(Histone acetylation);Histone Modification(acetylation editor);Located in the nucleus. | Q9NRC8 | NAD-dependent protein deacetylase sirtuin-7 | 51547 | B-WICH;sirtuin family;Histone deacetylases;HDAC | 31970414.. | Histone Modifier | Eraser | Unkown | |
| SKP1 | Histone modification write cofactor(Histone ubiquitination) | P63208 | S-phase kinase-associated protein 1 | 6500 | BCOR | 11961546.. | Histone Modifier | Writer | Unkown | |
| SLF1 | Histone modification read | Q9BQI6 | SMC5-SMC6 complex localization factor protein 1 | 84250 | Unkown | 33948371 | Histone Modifier | Reader | Unkown | |
| SMARCA1 | Chromatin remodelling, Histone modification erase( Histone acetylation);Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | P28370 | SMARCA1 protein | 6594 | NuRF, CERF, CERF;SWI/SNF family;ATP-dependent chromatin remodelling;SNF2-5 | 32572232.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| SMARCA2 | Histone modification read, TF( TF activator);Catalytic component of SWI/SNIF complex | P51531 | Probable global transcription activator SNF2L2 | 6595 | BAF, nBAF, npBAF, WINAC, bBAF, SWI/SNF BRM-BRG1;ATP-dependent chromatin remodelling;Bromo-PHD;Bromo-PHD | 33896578.. | Histone Modifier | Reader | Unkown | |
| SMARCA4 | Histone modification read, TF( TF activator);Nucleosome Positioning and Remodeling(Chromatin remodelling helicase);Essential for the maintenance of multipotent neural stem cells;Remodeler | P51532 | Transcription activator BRG1 | 6597 | BAF, nBAF, npBAF, PBAF, SWI/SNF_Brg1(I), SWI/SNF_Brg1(II), SWI/SNF_Brm, SWI/SNF-like_EPAFa, WINAC, SWI/SNF-like EPAFB, bBAF, SWI/SNF BRM-BRG1, CREST-BRG1;SWI/SNF family;ATP-dependent chromatin remodelling;Bromo-PHD | 34262032.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| SMARCA5 | Chromatin remodelling;Nucleosome Positioning and Remodeling(Chromatin remodelling helicase);Required for replication of pericentric heterochromatin in S-phase specifically in conjunction with BAZ1A | O60264 | Uncharacterized protein SMARCA5 | 8467 | ISWI; SNF2H; hISWI; hSNF2H; WCRF135 | 32756943.. | Chromatin Remodeler | Unkown | Unkown | |
| SMARCAD1 | Chromatin remodelling | Q9H4L7 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-containing DEAD/H box 1 | 56916 | ETL1; HEL1; ADERM | 30902974.. | Chromatin Remodeler | Unkown | Unkown | |
| SMARCAL1 | Chromatin remodelling | Q9NZC9 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (HepA-related protein) (Sucrose nonfermenting protein 2-like 1) | 50485 | HARP; HHARP | 30610086.. | Chromatin Remodeler | Unkown | Unkown | |
| SMARCB1 | Histone modification read;Nucleosome Positioning and Remodeling(Chromatin remodelling helicase);Remodeler | Q12824 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 | 6598 | BAF, nBAF, npBAF, PBAF, SWI/SNF_Brg1(I), SWI/SNF_Brg1(II), SWI/SNF_Brm, SWI/SNF-like_EPAFa, WINAC, SWI/SNF-like EPAFB, bBAF, SWI/SNF BRM-BRG1;SWI/SNF family;ATP-dependent chromatin remodelling;SNF2-5;SNF2-5 | 31759698.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| SMARCC1 | Chromatin remodelling cofactor;Remodeler | Q92922 | SWI/SNF complex subunit SMARCC1 | 6599 | Rsc8; SRG3; SWI3; BAF155; CRACC1 | 34937564 | Chromatin Remodeler | Unkown | Unkown | |
| SMARCC2 | Chromatin remodelling cofactor;Remodeler | Q8TAQ2 | SWI/SNF complex subunit SMARCC2 | 6601 | Rsc8; BAF170; CRACC2 | 33024572.. | Chromatin Remodeler | Unkown | Unkown | |
| SMARCD1 | Chromatin remodelling | Q96GM5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 | 6602 | Rsc6p; BAF60A; CRACD1 | 31992292.. | Chromatin Remodeler | Unkown | Unkown | |
| SMARCD2 | Chromatin remodelling cofactor | Q92925 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 | 6603 | Rsc6p; BAF60B; CRACD2; PRO2451 | 28442792.. | Chromatin Remodeler | Unkown | Unkown | |
| SMARCD3 | Chromatin remodelling cofactor | Q6STE5 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3 | 6604 | Rsc6p; BAF60C; CRACD3 | 35562902 | Chromatin Remodeler | Unkown | Unkown | |
| SMARCE1 | Chromatin remodelling cofactor | Q969G3 | SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 | 6605 | BAF57 | 28377514.. | Chromatin Remodeler | Unkown | Unkown | |
| SMC1A | Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q14683 | Structural maintenance of chromosomes protein 1A | 8243 | structural maintenance of chromosomes 1A | 33627431.. | Histone Modifier | Reader | Unkown | |
| SMCHD1 | Histone Modification(Acetylation, methylation and phosphorylation Reader) | A6NHR9 | Structural maintenance of chromosomes flexible hinge domain-containing protein 1 | 23347 | structural maintenance of chromosomes flexible hinge domain containing 1 | 33523915.. | Histone Modifier | Reader | Unkown | |
| SMYD1 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4 HMT | Q8NB12 | Hypothetical rhabdomyosarcoma antigen MU-RMS-40.9A | 150572 | SET and MYND domain containing;Histone methyltransferases;SET-HMT | 30061404.. | Histone Modifier | Writer | Unkown | |
| SMYD2 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4me, H3K36me2 HMT. Also methylates TP53 and RB1 | Q9NRG4 | N-lysine methyltransferase SMYD2 | 56950 | SET and MYND domain containing;Histone methyltransferases;SET-HMT | 33935284.. | Histone Modifier | Writer | Unkown | |
| SMYD3 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K4me2/me3 HMT | Q9H7B4 | Histone-lysine N-methyltransferase SMYD3 | 64754 | SET and MYND domain containing;Histone methyltransferases;SET-HMT | 30544196.. | Histone Modifier | Writer | Unkown | |
| SMYD4 | Histone modification erase cofactor(Histone acetylation);Histone Modification(Histone methyltransferases(HMT)) | Q8IYR2 | SET and MYND domain-containing protein 4 | 114826 | SET and MYND domain containing;SET-HMT | 32154082.. | Histone Modifier | Eraser | Unkown | |
| SNAI2 | Histone modification erase cofactor | O43623 | Zinc finger protein SNAI2 | 6591 | Unkown | 33420019.. | Histone Modifier | Eraser | Unkown | |
| SP1 | Chromatin remodelling, TF, TF( TF activator, TF repressor) | P08047 | Alternative protein SP1 | 6667 | 33069434.. | Chromatin Remodeler | Unkown | Unkown | ||
| SP100 | Chromatin remodelling cofactor | P23497 | Nuclear autoantigen Sp-100 | 6672 | lysp100b | 28439026.. | Chromatin Remodeler | Unkown | Unkown | |
| SP110 | Unkown | Q9HB58 | SP110 nuclear body protein | 3431 | IPR1; VODI; IFI41; IFI75 | 29642903 | Histone Modifier | Unkown | Unkown | |
| SP140 | Histone modification read, TF | Q13342 | Nuclear body protein SP140 | 11262 | Bromo-PHD | 35952671.. | Histone Modifier | Reader | Unkown | |
| SPEN | Histone modification erase cofactor, TF, TF(Histone acetylation, TF activator, TF repressor) | Q96T58 | Msx2-interacting protein | 23013 | MINT; SHARP; RBM15C; HIAA0929 | 32025035.. | Histone Modifier | Eraser | Unkown | |
| SPOP | Histone modification write(Histone ubiquitination) | O43791 | Speckle-type POZ protein | 8405 | TEF2; BTBD32 | 29160310.. | Histone Modifier | Writer | Unkown | |
| SRCAP | Chromatin remodelling, Histone modification erase( Histone acetylation);Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | Q6ZRS2 | Helicase SRCAP | 10847 | NuA4-related complex, SRCAP;Snf2-related CREBBP activator protein | 34349258.. | Histone Modifier,Chromatin Remodeler | Eraser | Unkown | |
| SS18L1 | Chromatin remodelling | Q75177 | Calcium-responsive transactivator | 26039 | CREST; LP2261 | 31522742 | Chromatin Remodeler | Unkown | Unkown | |
| SS18L2 | Chromatin remodelling | Q9UHA2 | SS18-like protein 2 (SYT homolog 2) | 51188 | KIAA-iso | 28514442.. | Chromatin Remodeler | Unkown | Unkown | |
| SSRP1 | Chromatin remodelling | Q08945 | FACT complex subunit SSRP1 | 6749 | FACT; T160; FACT80 | 28416484.. | Chromatin Remodeler | Unkown | Unkown | |
| STK4 | Histone modification write(Histone phosphorylation) | Q13043 | STK4 protein | 6789 | KRS2; MST1; YSK3; TIIAC | 33758424.. | Histone Modifier | Writer | Unkown | |
| SUDS3 | Histone modification erase cofactor(Histone acetylation) | Q9H7L9 | SUDS3 protein | 64426 | SDS3; SAP45 | 19070953.. | Histone Modifier | Eraser | Unkown | |
| SUPT16H | Histone modification read | Q9Y5B9 | FACT complex subunit | 11198 | CDC68; SPT16; FACTP140; SPT16/CDC68 | 33230303.. | Histone Modifier | Reader | Unkown | |
| SUPT3H | Histone modification write cofactor(Histone acetylation) | O75486 | Transcription initiation protein SPT3 homolog | 8464 | SPT3; SPT3L | 25934476.. | Histone Modifier | Writer | Unkown | |
| SUPT6H | Histone modification erase cofactor(Histone methylation) | Q7KZ85 | Transcription elongation factor SPT6 | 6830 | SPT6; SPT6H; emb-5 | 24441044.. | Histone Modifier | Eraser | Unkown | |
| SUV39H1 | Histone modification write, Histone modification write(Histone methylation, Histone phosphorylation);Histone Modification(Histone methyltransferases(HMT));H3K9me3 HMT, uses H3K9me1 as substrate | O43463 | Histone-lysine N-methyltransferase SUV39H1 | 6839 | eNoSc;suppressor of variegation 3-9;Histone methyltransferases;SET-HMT | 33643820.. | Histone Modifier | Writer | Unkown | |
| SUV39H2 | Histone modification write(Histone methylation);Histone Modification(Histone methyltransferases(HMT));H3K9me3 HMT, uses H3K9me1 as substrate | Q9H5I1 | Histone-lysine N-methyltransferase SUV39H2 | 79723 | suppressor of variegation 3-9;Histone methyltransferases | 33604655.. | Histone Modifier | Writer | Unkown | |
| SUZ12 | Histone modification write cofactor, Histone modification write cofactor, Polycomb group (PcG) protein, TF(Histone methylation, Histone ubiquitination, TF repressor);Histone Modification(chromatin silencing);Required for PRC2 H3K27 HMT activity. Interacts with SIRT1. | Q15022 | Polycomb protein SUZ12 | 23512 | PRC2;Polycomb group protein;Polycomb Repressive Complex 2(EZH2 coenzyme );Polycomb group | 32796172.. | Histone Modifier | Writer | Unkown | |
| TADA2A | Histone modification read, TF( TF activator) | O75478 | Transcriptional adapter 2-alpha | 6871 | ADA2; ADA2A; KL04P; hADA2; TADA2L | 32694556.. | Histone Modifier | Reader | Unkown | |
| TADA2B | Histone modification write cofactor(Histone acetylation) | Q86TJ2 | Transcriptional adapter 2-beta | 93624 | ADA2B; ADA2(beta) | 18936164.. | Histone Modifier | Writer | Unkown | |
| TADA3 | Histone modification write cofactor(Histone acetylation) | O75528 | Transcriptional adapter 3 (ADA3 homolog) (Transcriptional adapter 3-like) | 10474 | ADA3; NGG1; hADA3; STAF54; TADA3L | 23167988.. | Histone Modifier | Writer | Unkown | |
| TAF1 | Histone modification write(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation) | P21675 | Transcription initiation factor TFIID subunit | 6872 | CHD8, MLL2/3, MLL4/WBP7;TATA box binding protein (TBP)-associated factor;Bromo-PHD | 31664040.. | Histone Modifier | Writer | Unkown | |
| TAF10 | Histone chaperone, Histone modification write( Histone acetylation) | Q12962 | Transcription initiation factor TFIID subunit 10 | 6881 | TAF2A; TAF2H; TAFII30 | 25959397.. | Histone Modifier | Writer | Unkown | |
| TAF12 | Histone chaperone, Histone modification write( Histone acetylation) | Q16514 | Transcription initiation factor TFIID subunit 12 | 6883 | TAF2J; TAFII20 | 25965574.. | Histone Modifier | Writer | Unkown | |
| TAF1L | Histone modification read | Q8IZX4 | Transcription initiation factor TFIID subunit 1-like (TAF(II)210) (TBP-associated factor 1-like) (TBP-associated factor 210 kDa) (Transcription initiation factor TFIID 210 kDa subunit) | 138474 | Bromo-PHD | 29351916.. | Histone Modifier | Reader | Unkown | |
| TAF3 | Histone modification read;Histone Modification(K4 reader);Reader | Q5VWG9 | Transcription initiation factor TFIID subunit 3 | 83860 | TATA box binding protein (TBP)-associated factor | 23452851.. | Histone Modifier | Reader | Unkown | |
| TAF5 | Histone modification write cofactor(Histone acetylation) | Q15542 | Transcription initiation factor TFIID subunit 5 | 6877 | TAF2D; TAFII100 | 17227857.. | Histone Modifier | Writer | Unkown | |
| TAF5L | Histone modification write cofactor(Histone acetylation) | O75529 | TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L | 27097 | PAF65B | 31005419.. | Histone Modifier | Writer | Unkown | |
| TAF7 | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation) | Q15545 | Transcription initiation factor TFIID subunit 7 | 6879 | TAF2F; TAFII55 | 34890234.. | Histone Modifier | Writer | Unkown | |
| TBL1XR1 | Associates with HDAC3 | Q9BZK7 | F-box-like/WD repeat-containing protein TBL1XR1 | 79718 | C21; DC42; IRA1; TBLR1 | 32619424 | Histone Modifier | Unkown | Unkown | |
| TDG | DNA modification(DNA hydroxymethylation);DNA modification(DNA methylation editor/eraser);Essential for DNA demethylation | Q13569 | G/T mismatch-specific thymine DNA glycosylase | 6996 | TDG/mug DNA glycosylase family;DNA demethylases | 24153300.. | DNA Methylator | Unkown | Eraser | |
| TDRD3 | Histone modification read | Q9H7E2 | Tudor domain-containing protein 3 | 81550 | TUDOR | 28101374.. | Histone Modifier | Reader | Unkown | |
| TDRD7 | Histone modification read | Q8NHU6 | Tudor domain-containing protein 7 | 23424 | TUDOR | 33651978.. | Histone Modifier | Reader | Unkown | |
| TET1 | DNA modification(DNA hydroxymethylation);DNA modification(DNA methylation editor/eraser);Putative role in DNA demethylation | Q8NFU7 | Methylcytosine dioxygenase TET1 | 80312 | Ten-eleven translocation methylcytosine dioxygenase (TET);DNA demethylases(Converts 5mC to 5hmC) | 19372391.. | DNA Methylator | Unkown | Eraser | |
| TET2 | DNA modification(DNA hydroxymethylation);DNA modification(DNA methylation editor/eraser);Putative role in DNA demethylation | Q6N021 | Methylcytosine dioxygenase TET (EC 1.14.11.n2) | 54790 | Ten-eleven translocation methylcytosine dioxygenase (TET);DNA demethylases | 29364877.. | DNA Methylator | Unkown | Eraser | |
| TET3 | DNA modification(DNA hydroxymethylation);DNA modification(DNA methylation editor/eraser) | O43151 | Methylcytosine dioxygenase TET (EC 1.14.11.n2) | 200424 | Ten-eleven translocation methylcytosine dioxygenase (TET) | 35585240.. | DNA Methylator | Unkown | Eraser | |
| TEX10 | Histone modification write cofactor, Histone modification write cofactor(Histone methylation, Histone acetylation) | Q9NXF1 | Testis-expressed protein 10 | 54881 | Ipi1; bA208F1.2 | 25936917.. | Histone Modifier | Writer | Unkown | |
| TFPT | Chromatin remodelling cofactor, DNA modification( DNA hydroxymethylation);Putative regulatory component of the INO80 complex | P0C1Z6 | TCF3 fusion partner | 29844 | FB1; amida; INO80F | 17041757.. | Chromatin Remodeler | Unkown | ||
| TLE4 | Histone modification erase cofactor, TF | Q04727 | Transducin-like enhancer protein 4 | 7091 | ESG; BCE1; ESG4; GRG4; BCE-1; Grg-4; E(spI) | 29869113.. | Histone Modifier | Eraser | Unkown | |
| TLK1 | Histone modification write(Histone phosphorylation) | Q9UKI8 | Uncharacterized protein TLK1 | 9874 | PKU-beta | 30928383.. | Histone Modifier | Writer | Unkown | |
| TLK2 | Histone modification write(Histone phosphorylation) | Q86UE8 | Serine/threonine-protein kinase tousled-like 2 | 11011 | HsHPK; PKU-ALPHA | 29861108.. | Histone Modifier | Writer | Unkown | |
| TNP1 | Chromatin remodelling | P09430 | Spermatid nuclear transition protein 1 (STP-1) (TP-1) | 7141 | TP1 | 17943087.. | Chromatin Remodeler | Unkown | Unkown | |
| TNP2 | Chromatin remodelling | Q05952 | Nuclear transition protein 2 (TP-2) (TP2) | 7142 | TP2 | 34235877 | Chromatin Remodeler | Unkown | Unkown | |
| TONSL | Chromatin remodelling | Q96HA7 | Tonsoku-like protein | 4796 | IKBR; NFKBIL2 | 27338793.. | Chromatin Remodeler | Unkown | Unkown | |
| TOP2A | Chromatin remodelling | P11388 | DNA topoisomerase 2 (EC 5.6.2.2) | 7153 | TOP2; TP2A | 33296677.. | Chromatin Remodeler | Unkown | Unkown | |
| TOP2B | Chromatin remodelling | Q02880 | DNA topoisomerase 2 (EC 5.6.2.2) | 7155 | TOPIIB; top2beta | 34753908.. | Chromatin Remodeler | Unkown | Unkown | |
| TP53 | Histone modification write cofactor, TF, TF(Histone acetylation, TF activator, TF repressor) | P04637 | Tumor suppressor p53 | 7157 | P53; BCC7; LFS1; TRP53 | 33649166.. | Histone Modifier | Writer | Unkown | |
| TP53BP1 | Histone modification read;Histone Modification(K79 reader) | Q12888 | TP53-binding protein 1 | 7158 | tumor protein p53 binding protein 1;TUDOR | 24326623.. | Histone Modifier | Reader | Unkown | |
| TRIM16 | Histone modification write(Histone acetylation) | O95361 | Tripartite motif-containing protein 16 | 10626 | EBBP | 35437018.. | Histone Modifier | Writer | Unkown | |
| TRIM24 | Histone modification read | O15164 | Transcription intermediary factor 1-alpha | 8805 | Bromo-PHD | 32895234.. | Histone Modifier | Reader | Unkown | |
| TRIM27 | Histone modification erase cofactor(Histone acetylation) | P14373 | Zinc finger protein RFP | 5987 | RFP; RNF76 | 33251042.. | Histone Modifier | Eraser | Unkown | |
| TRIM28 | Histone modification read;Mediates silencing by recruiting SET1 H3K9me3 HMT and HDAC NuRD complex. Mediates apoptosis through degradation of p53 | Q13263 | Transcription intermediary factor 1-beta | 10155 | Histone methyltransferases | 34419074.. | Histone Modifier | Reader | Unkown | |
| TRIM33 | Histone modification read | Q9UPN9 | E3 ubiquitin-protein ligase TRIM33 | 51592 | Unkown | 32184320.. | Histone Modifier | Reader | Unkown | |
| TRRAP | Histone modification write cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9Y4A5 | Transformation/transcription domain-associated protein | 8295 | SWR, PCAF, TFTC-HAT, NuA4, SAGA, NuA4-related complex, STAGA;phosphoinositide 3-kinase-related kinases (PIKK) family;HAT | 29653964.. | Histone Modifier | Reader,Writer | Unkown | |
| TSSK6 | Histone modification write(Histone phosphorylation) | Q9BXA6 | Testis-specific serine/threonine-protein kinase 6 | 83983 | CT72; SSTK; TSSK4; FKSG82 | 28389581 | Histone Modifier | Writer | Unkown | |
| TTF2 | Nucleosome Positioning and Remodeling(Chromatin remodelling helicase) | Q9UNY4 | Transcription termination factor 2 | 8458 | HuF2; ZGRF6 | 24105688 | Chromatin Remodeler | Unkown | Unkown | |
| TTK | Histone modification write cofactor(Histone phosphorylation) | P33981 | Dual-specificity protein kinase TTK | 7272 | ESK; PYT; CT96; MPH1; MPS1; MPS1L1 | 31961339.. | Histone Modifier | Writer | Unkown | |
| UBE2A | Histone modification write(Histone ubiquitination) | P49459 | Ubiquitin-conjugating enzyme E2 A | 7319 | UBC2; HHR6A; MRXSN; RAD6A; MRXS30 | 30531907.. | Histone Modifier | Writer | Unkown | |
| UBE2B | Histone modification write(Histone ubiquitination) | P63146 | Ubiquitin-conjugating enzyme E2 B | 7320 | HR6B; UBC2; HHR6B; RAD6B; E2-17kDa | 31576007.. | Histone Modifier | Writer | Unkown | |
| UBE2D1 | Histone modification write(Histone ubiquitination) | P51668 | Ubiquitin-conjugating enzyme E2 D1 | 7321 | SFT; UBCH5; UBC4/5; UBCH5A; E2(17)KB1 | 30482241.. | Histone Modifier | Writer | Unkown | |
| UBE2D3 | Histone modification write(Histone ubiquitination) | P61077 | Ubiquitin-conjugating enzyme E2 D3 | 7323 | UBC4/5; UBCH5C; E2(17)KB3 | 28469175.. | Histone Modifier | Writer | Unkown | |
| UBE2E1 | Histone modification write(Histone ubiquitination) | P51965 | Ubiquitin-conjugating enzyme E2 E1 | 7324 | UBCH6 | 27855695.. | Histone Modifier | Writer | Unkown | |
| UBE2H | Histone modification write(Histone ubiquitination) | P62256 | Ubiquitin-conjugating enzyme E2 H | 7328 | GID3; UBC8; UBCH; UBCH2; E2-20K | 30244854.. | Histone Modifier | Writer | Unkown | |
| UBE2N | Histone modification write(Histone ubiquitination) | P61088 | Ubiquitin-conjugating enzyme E2 N | 7334 | UBC13; UbcH13; HEL-S-71; UbcH-ben; UBCHBEN; UBC13 | 35263148.. | Histone Modifier | Writer | Unkown | |
| UBE2T | Histone modification write(Histone ubiquitination) | Q9NPD8 | Ubiquitin-conjugating enzyme E2 T | 29089 | FANCT; PIG50; HSPC150 | 31481791.. | Histone Modifier | Writer | Unkown | |
| UBN1 | Histone modification write cofactor(Histone methylation) | Q9NPG3 | Ubinuclein-1 | 29855 | VT; VT4 | 30285846 | Histone Modifier | Writer | Unkown | |
| UBR2 | Histone modification write(Histone ubiquitination) | Q8IWV8 | E3 ubiquitin-protein ligase UBR2 | 23304 | C6orf133; bA49A4.1; dJ242G1.1; dJ392M17.3 | 31268597.. | Histone Modifier | Writer | Unkown | |
| UBR5 | Chromatin remodelling, Histone modification write cofactor( Histone ubiquitination) | O95071 | UBR5 protein | 51366 | DD5; EDD; HYD; EDD1 | 33293516.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | |
| UCHL5 | Histone modification erase cofactor(Histone ubiquitination) | Q9Y5K5 | Ubiquitin carboxyl-terminal hydrolase isozyme L5 | 51377 | UCH37; CGI-70; INO80R; UCH-L5 | 33156996.. | Histone Modifier | Eraser | Unkown | |
| UHRF1 | Histone modification read, Histone modification write cofactor(Histone ubiquitination);DNA modification(DNA methylation reader) | Q96T88 | Alternative protein UHRF1 | 29128 | ubiquitin-like with PHD and ring finger domains 1;RING finger | 34561619.. | DNA Methylator,Histone Modifier | Reader,Writer | Reader | |
| UHRF2 | Histone modification read | Q96PU4 | E3 ubiquitin-protein ligase UHRF2 | 115426 | RING finger | 34111398.. | Histone Modifier | Reader | Unkown | |
| UIMC1 | Histone modification read | Q96RL1 | BRCA1-A complex subunit RAP80 | 51720 | RAP80; X2HRIP110 | 17562356 | Histone Modifier | Reader | Unkown | |
| USP11 | Histone modification erase cofactor(Histone ubiquitination) | P51784 | Ubiquitin carboxyl-terminal hydrolase 11 | 8237 | UHX1 | 34526504.. | Histone Modifier | Eraser | Unkown | |
| USP12 | Histone modification erase(Histone ubiquitination) | O75317 | Ubiquitin carboxyl-terminal hydrolase 12 | 219333 | UBH1; USP12L1 | 34381028.. | Histone Modifier | Eraser | Unkown | |
| USP15 | Histone modification erase(Histone ubiquitination) | Q9Y4E8 | Ubiquitin carboxyl-terminal hydrolase 15 | 9958 | UNPH4; UNPH-2 | 31477895.. | Histone Modifier | Eraser | Unkown | |
| USP16 | Histone modification erase(Histone ubiquitination) | Q9Y5T5 | Ubiquitin carboxyl-terminal hydrolase 16 | 10600 | UBPM; UBP-M | 24025767.. | Histone Modifier | Eraser | Unkown | |
| USP17L2 | Histone modification erase cofactor(Histone ubiquitination) | Q6R6M4 | Ubiquitin carboxyl-terminal hydrolase 17 | 377630 | DUB3; DUB-3; USP17 | 36040642 | Histone Modifier | Eraser | Unkown | |
| USP21 | Histone modification erase(Histone ubiquitination) | Q9UK80 | Ubiquitin carboxyl-terminal hydrolase 21 | 27005 | USP16; USP23 | 31488580.. | Histone Modifier | Eraser | Unkown | |
| USP22 | Histone modification write cofactor(Histone ubiquitination) | Q9UPT9 | Ubiquitin carboxyl-terminal hydrolase 22 | 23326 | USP3L | 31776228.. | Histone Modifier | Writer | Unkown | |
| USP3 | Histone modification write(Histone ubiquitination) | Q9Y6I4 | Ubiquitin carboxyl-terminal hydrolase 3 | 9960 | UBP; SIH003 | 24366338.. | Histone Modifier | Writer | Unkown | |
| USP36 | Histone modification write cofactor(Histone ubiquitination) | E9PEW0 | Ubiquitin carboxyl-terminal hydrolase 36 | 57602 | DUB1 | 33237263.. | Histone Modifier | Writer | Unkown | |
| USP44 | Histone modification erase(Histone ubiquitination) | Q9H0E7 | Ubiquitin carboxyl-terminal hydrolase 44 | 84101 | 35079021.. | Histone Modifier | Eraser | Unkown | ||
| USP46 | Histone modification erase(Histone ubiquitination) | P62068 | Ubiquitin carboxyl-terminal hydrolase 46 | 64854 | 31632687.. | Histone Modifier | Eraser | Unkown | ||
| USP49 | Histone modification erase(Histone ubiquitination) | Q70CQ1 | Ubiquitin carboxyl-terminal hydrolase 49 | 25862 | 28363942.. | Histone Modifier | Eraser | Unkown | ||
| USP7 | Histone modification erase, DNA modification cofactor(Histone ubiquitination, DNA methylation) | Q93009 | Ubiquitin carboxyl-terminal hydrolase 7 | 7874 | TEF1; HAUSP | 29045385.. | DNA Methylator,Histone Modifier | Eraser | Unkown | |
| UTY | Histone modification erase(Histone ubiquitination);Histone Modification(Histone demethylase (HDM));H3K27me3/me2/me1 HDM. | O14607 | Ubiquitously transcribed tetratricopeptide repeat protein Y-linked transcript variant 37 | 7404 | ubiquitously transcribed tetratricopeptide repeat containing, Y-linked;Histone demethylases | 34526716.. | Histone Modifier | Eraser | Unkown | |
| VDR | Chromatin remodelling cofactor, TF | P11473 | Vitamin D receptor | 7421 | NR1I1; PPP1R163 | 25452584.. | Chromatin Remodeler | Unkown | Unkown | |
| VPS72 | Histone modification write cofactor(Histone acetylation) | Q15906 | Vacuolar protein sorting-associated protein 72 homolog | 6944 | NuA4, NuA4-related complex | 26974126.. | Histone Modifier | Writer | Unkown | |
| VRK1 | Histone modification write(Histone phosphorylation) | Q99986 | Serine/threonine-protein kinase VRK1 | 7443 | PCH1; PCH1A | 33516791 | Histone Modifier | Writer | Unkown | |
| WAC | Histone modification write cofactor(Histone ubiquitination) | Q9BTA9 | WW domain-containing adapter protein with coiled-coil | 51322 | Wwp4; BM-016; PRO1741 | 21329877.. | Histone Modifier | Writer | Unkown | |
| WDR5 | Histone modification read;Complex with MLL.;Writer | P61964 | WD repeat-containing protein 5 | 11091 | ATAC, NSL, RING2-L3MBTL2, COMPASS, Menin-associated_HMT, MLL-HCF, CHD8, MLL2/3, COMPASS-like MLL1,2, MLL4/WBP7, COMPASS-like MLL3,4;Histone methyltransferases;WD-40 | 31685992.. | Histone Modifier | Reader,Writer | Unkown | |
| WDR77 | Histone modification write(Histone methylation) | Q9BQA1 | Methylosome protein 50 | 79084 | p44; MEP50; MEP-50; HKMT1069; Nbla10071; p44/Mep50 | 28977470.. | Histone Modifier | Writer | Unkown | |
| WDR82 | Histone modification write cofactor(Histone methylation) | Q6UXN9 | WD repeat-containing protein 82 | 80335 | SWD2; MST107; WDR82A; MSTP107; PRO2730; TMEM113; PRO34047 | 29269482.. | Histone Modifier | Writer | Unkown | |
| WHSC1 | Histone modification write(Histone methylation);Histone Modification(K36 writer);Writer | O96028 | Alternative protein WHSC1 | 7468 | WHS; NSD2; TRX5; MMSET; REIIBP | 31235934.. | Histone Modifier | Writer | Unkown | |
| WHSC1L1 | Chromatin remodelling cofactor, TF | Q9BZ95 | Histone-lysine N-methyltransferase NSD3 | 54904 | NSD3; pp14328 | 27005559 | Chromatin Remodeler | Unkown | Unkown | |
| WSB2 | Histone modification write(Histone ubiquitination) | Q9NYS7 | WD repeat and SOCS box-containing protein 2 | 55884 | SBA2 | 32945370 | Histone Modifier | Writer | Unkown | |
| YAF2 | Chromatin remodelling cofactor | Q8IY57 | YY1-associated factor 2 | 10138 | 32203418.. | Chromatin Remodeler | Unkown | Unkown | ||
| YEATS4 | Histone modification write cofactor(Histone acetylation) | O95619 | YEATS domain-containing protein 4 | 8089 | NuA4, NuA4-related complex, SRCAP;YEATS | 34349258.. | Histone Modifier | Writer | Unkown | |
| YWHAB | Histone modification erase cofactor(Histone acetylation) | P31946 | 14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed] | 7529 | HS1; GW128; YWHAA; KCIP-1; HEL-S-1 | 30317584 | Histone Modifier | Eraser | Unkown | |
| YWHAE | Histone modification erase cofactor(Histone acetylation) | P62258 | 14-3-3 protein epsilon | 7531 | MDS; HEL2; MDCR; KCIP-1; 14-3-3E | 33947829 | Histone Modifier | Eraser | Unkown | |
| YWHAZ | Histone modification read | P63104 | 14-3-3 protein zeta/delta | 7534 | HEL4; YWHAD; KCIP-1; HEL-S-3; HEL-S-93; 14-3-3-zeta | 29858089.. | Histone Modifier | Reader | Unkown | |
| YY1 | Chromatin remodelling cofactor, TF( TF repressor);Also interacts with PRC2 and is required for EZH2-mediated H3K27me3 | P25490 | Transcriptional repressor protein YY1 | 7528 | DELTA; NF-E1; UCRBP; INO80S; YIN-YANG-1 | 29224777.. | Chromatin Remodeler | Unkown | Unkown | |
| ZBTB16 | Histone modification erase cofactor(Histone acetylation) | Q05516 | Zinc finger and BTB domain-containing protein 16 | 7704 | PLZF; ZNF145 | 26916077.. | Histone Modifier | Eraser | Unkown | |
| ZBTB33 | Histone modification write cofactor, Histone modification erase cofactor, TF(Histone acetylation, Histone methylation, TF repressor);DNA modification(DNA methylation reader) | Q86T24 | Alternative protein ZBTB33 | 10009 | Zinc finger and BTB domain containing(ZBTB) | 33526872.. | DNA Methylator,Histone Modifier | Writer,Eraser | Reader | |
| ZBTB38 | DNA modification(DNA methylation reader) | Q8NAP3 | Zinc finger and BTB domain-containing protein 38 | 253461 | Zinc finger and BTB domain containing(ZBTB) | 34697293.. | DNA Methylator | Unkown | Reader | |
| ZBTB4 | DNA modification(DNA methylation reader) | Q9P1Z0 | ZBTB4 protein | 57659 | Zinc finger and BTB domain containing(ZBTB) | 27815388.. | DNA Methylator | Unkown | Reader | |
| ZCWPW1 | Histone modification read | Q9H0M4 | Zinc finger CW-type PWWP domain protein 1 | 55063 | PWWP | 31453335.. | Histone Modifier | Reader | Unkown | |
| ZGPAT | TF(TF repressor) | Q8N5A5 | Zinc finger CCCH-type with G patch domain-containing protein | 84619 | ZIP; ZC3H9; GPATC6; GPATCH6; ZC3HDC9; KIAA1847 | 33081725 | Chromatin Remodeler | Unkown | Unkown | |
| ZHX1 | Chromatin remodelling, Histone modification write cofactor, Histone modification write cofactor( Histone acetylation, Histone methylation) | Q9UKY1 | Zinc fingers and homeoboxes protein 1 | 11244 | 31648104.. | Histone Modifier,Chromatin Remodeler | Writer | Unkown | ||
| ZMYM1 | Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q5SVZ6 | Zinc finger MYM-type protein 1 | 79830 | zinc finger, MYM-type | 31607270 | Histone Modifier | Reader | Unkown | |
| ZMYM2 | Histone modification erase cofactor, TF(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9UBW7 | Zinc finger MYM-type protein 2 | 7750 | BHC, LSD-CoREST;zinc finger, MYM-type | 32032525.. | Histone Modifier | Reader,Eraser | Unkown | |
| ZMYM3 | Histone modification erase cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q14202 | Zinc finger MYM-type protein 3 | 9203 | BHC;zinc finger, MYM-type | 26200345.. | Histone Modifier | Reader,Eraser | Unkown | |
| ZMYM4 | Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q5VZL5 | Zinc finger MYM-type protein 4 | 9202 | zinc finger, MYM-type | 32492392.. | Histone Modifier | Reader | Unkown | |
| ZMYM5 | Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9UJ78 | Zinc finger MYM-type protein 5 | 9205 | zinc finger, MYM-type | 27431290.. | Histone Modifier | Reader | Unkown | |
| ZMYM6 | Histone Modification(Acetylation, methylation and phosphorylation Reader) | O95789 | Zinc finger MYM-type protein 6 | 9204 | zinc finger, MYM-type | 32025240 | Histone Modifier | Reader | Unkown | |
| ZMYND11 | Histone modification read(Histone methylation) | Q15326 | Zinc finger MYND domain-containing protein 11 (cDNA FLJ50504, highly similar to Mus musculus zinc finger, MYND domain containing 11 (Zmynd11), mRNA) | 10771 | Bromo-PHD | 32699416.. | Histone Modifier | Reader | Unkown | |
| ZMYND8 | Histone modification erase cofactor(Histone acetylation);Histone Modification(Acetylation, methylation and phosphorylation Reader) | Q9ULU4 | Protein kinase C-binding protein 1 | 23613 | zinc finger, MYND-type containing 8;Bromo-PHD;Bromo-PHD | 33932349.. | Histone Modifier | Reader,Eraser | Unkown | |
| ZNF217 | Histone modification erase cofactor, TF(Histone acetylation, TF repressor) | O75362 | Zinc finger protein 217 | 7764 | ZABC1 | 32721948.. | Histone Modifier | Eraser | Unkown | |
| ZNF516 | Histone modification erase cofactor, TF(Histone acetylation, TF repressor) | Q92618 | Zinc finger protein 516 | 9658 | HsT287 | 28947780 | Histone Modifier | Eraser | Unkown | |
| ZNF532 | Histone modification erase cofactor(Histone acetylation) | K7EIU3 | Zinc finger protein 532 | 55205 | 32343678.. | Histone Modifier | Eraser | Unkown | ||
| ZNF541 | Chromatin remodelling | Q9H0D2 | Zinc finger protein 541 | 84215 | 32296183.. | Chromatin Remodeler | Unkown | Unkown | ||
| ZNF592 | Histone modification erase cofactor(Histone acetylation) | Q92610 | Alternative protein ZNF592 | 9640 | CAMOS; SCAR5 | 26478897 | Histone Modifier | Eraser | Unkown | |
| ZNF687 | Histone modification erase cofactor(Histone acetylation) | H0Y5I5 | Zinc finger protein 687 | 57592 | 26849110.. | Histone Modifier | Eraser | Unkown | ||
| ZNF711 | Histone modification erase cofactor(Histone acetylation) | Q6PK66 | ZNF711 protein | 7552 | ZNF4; ZNF5; ZNF6; CMPX1; MRX97; Zfp711; dJ75N13.1 | 34521054 | Histone Modifier | Eraser | Unkown | |
| ZRANB3 | Chromatin remodelling, Histone modification read cofactor( Histone methylation) | Q5FWF4 | DNA annealing helicase and endonuclease ZRANB3 | 84083 | AH2; 4933425L19Rik | 28886337.. | Histone Modifier,Chromatin Remodeler | Reader | Unkown | |
| ZZZ3 | Histone modification read | Q8IYH5 | ZZ-type zinc finger-containing protein 3 | 26009 | ATAC1 | 30217978 | Histone Modifier | Reader | Unkown |